Synthetic polymers adsorbing bisphenol�A and its analogues prepared by covalent molecular imprinting using bisphenol�A dimethacrylate as a template molecule

Abstract

Synthetic polymers which can adsorb bisphenol A (BPA) and related compounds were prepared by a covalent molecular imprinting technique. BPA dimethacrylate, used as template molecule, was polymerized with a crosslinker, triethylene glycol dimethacrylate (TEGDMA) or trimethylol propane trimethacrylate (TRIM). After the polymerization treatment with dilute NaOH was used to cleave BPA from the polymers. For high recovery of BPA with low polymer matrix degradation, the hydrolysis conditions were determined to be treatment with 1.0 mol L(-1) NaOH for 48 h. The binding sites generated by the hydrolysis were evaluated by determination of the retentivity of BPA, BPA analogues, and other endocrine disruptors. The polymers strongly adsorbed compounds with two hydroxyl groups at the 4,4'-positions. Generally the TEGDMA-based polymers had stronger affinity than the TRIM-based polymers, although the TRIM-based polymer adsorbed steroidal hormones with two hydroxyl groups, for example 17 alpha-estradiol and 17 beta-estradiol, more strongly than the TEGDMA-based polymer, meaning that the crosslinkers affected the properties of the binding sites and, depending upon the target molecules, suitable crosslinkers should be chosen in this system.

Protein-imprinted polysiloxane scaffolds

“…Refs. [5][6][7][8][9][10]). Comparatively few reports describe imprinting inorganic materials [11][12][13][14][15][16].…”

Extraction Techniques for Isolation, Purification and Preconcentration of Bisphenols and Alkylphenols from Environmental and Food Samples

“…Molecularly imprinted polymers for phenolic compounds (bisphenols, alkylphenols and their derivatives) are usually obtained by non-covalent imprinting techniques [34-41, 82, 85, 86], while in the literature there are only a few reports about covalent or semi-covalent imprinting [39,[87][88][89]. The latter two techniques require the use of harsh conditions in order to remove target compounds which consequently can result in the partial degradation of the polymer matrix.…”

Bisphenol A Analog-Imprinted Polymers Prepared by an Immobilized Template on a Modified Silica Microsphere Matrix

“…2) was investigated by measuring their retention on imprinted polymers with a mobile phase of chloroform/acetonitrile (9:1 (v/v)). Because previously reported BPA-imprinted polymers exhibited high affinities for BPA and its structural analogue compounds, [14][15][16] we employed this condition. The results are shown in Fig.…”

“…Due to such characteristics, many research groups reported BPA-imprinted polymers prepared using various templates. [11][12][13][14][15][16] We report herein a BPA binding imprinted polymer that has been prepared by immobilization of the template, 4,4′-bis(4-hydroxyphenyl)valeric acid, to a silica matrix. This yielded imprinted polymers of uniform size and shape with structurally controlled binding sites.…”