Synthetic strategy for the incorporation of Bu2Sn(IV) into fluorinated β-diketones/benzoylacetone and sterically demanding heterocyclic β-diketones and spectroscopic characterization of hexacoordinated complexes of Bu2Sn(IV)

Maheshwari, Karuna; Jain, Asha; Saxena, Sanjiv

doi:10.1515/mgmc-2013-0049

Cited by 9 publications

(4 citation statements)

References 12 publications

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“…Various types of Schiff bases have been synthesized and extensively studied because of their antifungal, antiviral, antibacterial, anti‐tumour and anti‐inflammatory properties as well as their industrial and medicinal utility . Organotin(IV) complexes of β‐diketones, heterocyclic β‐diketones, Schiff bases, oximes, amino acids, sulfa drugs, etc., have been reported in the literature due to their potential industrial and biological applications . Organotin(IV) complexes of Schiff bases have attracted considerable interest owing to their biocidal and anti‐tumour activities and potential applications in organic synthesis, catalysis, medicinal chemistry and biotechnology .…”

Section: Introductionmentioning

confidence: 99%

Synthesis, characterization and antimicrobial activity of triorganotin(IV) derivatives of some bioactive Schiff base ligands

Bhatra

Sharma

et al. 2016

Applied Organom Chemis

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Triorganotin(IV) complexes of the type Me3Sn[OC(R1):CH(CH3)C:NR2OH] and Ph3Sn[OC(R′):CH(CH3)C:NR″OH] (R′ = ─CH3, ─C6H5; R″ = ─(CH2)2─, ─(CH2)3─) have been synthesized by the reactions of trimethyl/phenyltin(IV) chloride with the sodium salt of corresponding Schiff base ligands in unimolar ratio in refluxing tetrahydrofuran. All these compounds have been characterized using elemental analyses and their probable structures have been proposed on the basis of infrared, 1H NMR, 13C NMR, 119Sn NMR and mass spectroscopic studies. In the trimethyltin(IV) derivatives the central tin atom is tetracoordinated, whereas in the analogous triphenyltin(IV)derivatives the central tin atom is pentacoordinated. All these ligands, metal precursors and corresponding triorganotin(IV) complexes have been screened for antimicrobial activities. A comparison of activities of the ligands and their corresponding triorganotin(IV) derivatives has been made. Attempts have also been made to relate the activity to the structure of these compounds.

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Section: Introductionmentioning

confidence: 99%

Synthesis, characterization and antimicrobial activity of triorganotin(IV) derivatives of some bioactive Schiff base ligands

Bhatra

Sharma

et al. 2016

Applied Organom Chemis

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“…These compounds have interesting structural features (Sharma et al, 2007(Sharma et al, , 2010Gupta et al, 2010;Maheshwari et al, 2014) and demonstrate potential applications in catalysis, sorption (Adachi et al, 1997) and organic light emitting diodes (Garcia-Lopez et al, 2014). It has been reported that a new dimethyltin(IV) complex was used as a precursor for the preparation of SnO 2 nanoparticles which show photoluminescence (Najafi et al, 2013).…”

Section: Introductionmentioning

confidence: 99%

Synthesis of novel penta and hexa coordinated monobutyltin(IV) derivatives based on oximes and N-protected amino acids

Srivastava

Maheshwari

Jain

et al. 2015

Main Group Metal Chemistry

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Several new monobutyltin(IV) derivatives containing both oximes and N-protected amino acids have been generated. The compounds having the general formulae BuSn[(L) 2 A], where LH = cyclohexanoneoxime, acetophenoneoxime and AH = C(O)C 6 H 4 C(O)NCHRCOOH (where R = -CH(CH 3 ) 2 , -CH(CH 3 )CH 2 CH 3 , -CH 2 C 6 H 5 ), and BuSn[L(A) 2 ], where LH = cyclohexanoneoxime, acetophenoneoxime and AH = C(O)C 6 H 4 C(O)NCHRCOOH (where R = -CH(CH 3 ) 2 , -CH(CH 3 )CH 2 CH 3 , -CH 2 C 6 H 5 ), were generated by the reactions of monobutyltin(IV) trichloride with sodium salts of oximes and N-protected amino acids in 1:2:1 and 1:1:2 molar ratios in dry boiling benzene. Plausible structures of these compounds were suggested based on physico-chemical and spectroscopic studies. 119 Sn NMR spectroscopic data revealed the presence of five and six coordinated tin centers.

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“…The last few decades have witnessed important developments regarding the characterization of chemical structure based on spectroscopic studies . The chemical structure of a drug molecule may be related to its physiological action.…”

Section: Introductionmentioning

confidence: 99%

Investigation of pharmacophore and antipharmacophore features of certain dimethyltin(IV) complexes of flexible N‐protected amino acids and fluorinated β‐diketone/β‐diketones

Maheshwari

Srivastava

Saxena

et al. 2016

Applied Organom Chemis

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A set of pentacoordinated dimethyltin(IV) complexes of flexible N‐protected amino acids and fluorinated β‐diketone/β‐diketones was screened for their antibacterial activity against Pseudomonas aeruginosa, Staphylococcus aureus and Streptomyces griseus. These pentacoordinated complexes of the type Me2SnAB (where : R = CH(CH3)C2H5, A1H; CH2CH(CH3)2, A2H; CH(CH3)2, A3H; CH2C6H5, A4H; and BH = R'C(O)CH2C(O)R″: R′ = C6H5, R″ = CF3, B1H; R′ = R″ = CH3, B2H; R′ = C6H5, R″ = CH3, B3H; R′ = R″ = C6H5, B4H) were generated by the reactions of dimethyltin(IV) dichloride with sodium salts of flexible N‐protected amino acids (ANa) and fluorinated β‐diketone/β‐diketones (BNa) in 1:1:1 molar ratio in refluxing dry benzene solution. Plausible structures of these complexes were elucidated on the basis of physicochemical and spectral studies. 119Sn NMR spectral data revealed the presence of pentacoordinated tin centres in these dimethyltin(IV) complexes.

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Synthetic strategy for the incorporation of Bu2Sn(IV) into fluorinated β-diketones/benzoylacetone and sterically demanding heterocyclic β-diketones and spectroscopic characterization of hexacoordinated complexes of Bu2Sn(IV)

Cited by 9 publications

References 12 publications

Synthesis, characterization and antimicrobial activity of triorganotin(IV) derivatives of some bioactive Schiff base ligands

Synthesis, characterization and antimicrobial activity of triorganotin(IV) derivatives of some bioactive Schiff base ligands

Synthesis of novel penta and hexa coordinated monobutyltin(IV) derivatives based on oximes and N-protected amino acids

Investigation of pharmacophore and antipharmacophore features of certain dimethyltin(IV) complexes of flexible N‐protected amino acids and fluorinated β‐diketone/β‐diketones

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