Syphilitic aortic aneurysm presenting with upper airway obstruction

Waikittipong, Somchai

doi:10.1177/0218492311436257

Cited by 5 publications

(7 citation statements)

References 8 publications

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“…4 ). These above findings conformed to the pathological changes of the syphilitic arteritis [ 16 , 17 ]. Therefore, we believe the syphilitic arteritis contributes to the formation of femoral artery aneurysm.…”

Section: Discussionsupporting

confidence: 85%

Surgical treatment of syphilitic superficial femoral artery aneurysm: a rare case report

et al. 2015

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BackgroundArterial aneurysm is a known complication of syphilis, but the occurrence of femoral artery aneurysm secondary to the syphilitic disease has never been reported.Case presentationThe present study described a 60-year-old Chinese male who presented with two aneurysms in the middle and lower segment of the right superficial femoral artery causing the symptoms of pain, coldness and numbness in the right lower limb. This case was diagnosed with syphilitic superficial femoral aneurysm because of positive syphilitic testing and the inflammatory cell infiltration around the adventitial vasa vasorum under the pathological examination. Anti-syphilis treatment, stent graft implantation and open surgery were attempted to eliminate the syphilis and aneurysm, which was ultimately successful, with no symptoms after a follow-up of 3 months.ConclusionCombined open and endovascular repair may be effective and safe for treatment of syphilitic femoral artery aneurysms.

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Section: Discussionsupporting

confidence: 85%

Surgical treatment of syphilitic superficial femoral artery aneurysm: a rare case report

et al. 2015

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“…In 1952 the thoracic/abdominal aneurysms ratio was 2 : 1, until 1964 when this ratio equalised, making the syphilitic cardiovascular involvement very rare in current days [8]. …”

Section: Discussionmentioning

confidence: 99%

“…Cardiovascular syphilis is characterised by obliterating endarteritis, which may affect small-calibre vases irrespective of location, but it is much more devastating whenever it affects the aorta’s vasa vasorum , jeopardising the blood supply of the aortic wall, leading to destruction of the elastic tissue and weakening of the medial aortic tunic, particularly in the ascendant and transverse segments of the thoracic aortic arc [3, 8–10, 12]. The macroscopic aspect is classically described as “tree bark” due to inner layer alterations and parietal calcification [7, 10, 11].…”

Section: Discussionmentioning

confidence: 99%

“…Classically, syphilitic aneurysms occur in 90% of cases on the thoracic aorta, and in 10% in the abdominal aorta [3, 7–9]. Infection of aortic wall develops during the secondary or bacteraemic phase of syphilis, having a latent period from infection until the clinical presentation ranging from 5 to 50 years [5, 8]. …”

Section: Introductionmentioning

confidence: 99%

“…There is also obstruction due to granuloma formation and focal necrosis of the elastic and muscular layers ad substitution for fibrotic tissue that afterwards turns into calcification (syphilitic aorta) [10, 11]. This process may carry on and generate extreme strictures with saccular or fusiform aneurysms [8–10]. Due to intense scarring of the media layer, rupture resulting from a dissection is highly unlikely to occur, as opposed as non-syphilitic aortic aneurysms, in which the rupture is the main cause of death.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Aortic aneurysm in a patient with syphilis-related spinal pain and paraplegia

Araújo

Oliveira

Rovere³

et al. 2017

Reumatologia

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The tertiary stage of syphilis is nowadays extremely rare, showing predilection for the cardiovascular and nervous systems.A 57-year-old Caucasian man sought medical assistance due to back pain that evolved to paraplegia of the lower limbs. A thoracic CT scan demonstrated an important aneurysmatic lesion of the descending thoracic aorta causing erosion of the vertebral bodies and VDRL and FTA-abs positivity.Although rare, syphilitic aortitis, the hallmark of cardiovascular syphilis, should be considered in the differential diagnosis in patients with thoracic aneurysm when in the absence of classic risk factors for atherosclerosis, especially in cases that progress with erosion of vertebral bodies.

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Syphilitic aortic aneurysm

Yuan

2018

Z Rheumatol

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The aim of this study was to outline the clinical features of syphilitic aortic aneurysm. The study materials were based on a comprehensive literature review of publications on syphilitic aortic aneurysm published between 2000 and 2017. Syphilitic aortic aneurysm occurred most commonly in the ascending aorta in either a saccular or a fusiform shape. Syphilitic aortic aneurysm was often complicated by aortic valve insufficiency (in almost half of the patients), and by a coronary artery/ostium lesion in 16.5% of the patients. Aortic valve operation was necessary in one fourth, and coronary artery surgery accounted for less than one fifth of patients warranting a surgical treatment. Although there was no difference in the survival rates between the surgically and conservatively treated patients, an aggressive treatment should be performed when diagnosis is made due to the potential risks of aneurysm rupture and sudden death.

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Syphilitic aortic aneurysm presenting with upper airway obstruction

Cited by 5 publications

References 8 publications

Surgical treatment of syphilitic superficial femoral artery aneurysm: a rare case report

Surgical treatment of syphilitic superficial femoral artery aneurysm: a rare case report

Aortic aneurysm in a patient with syphilis-related spinal pain and paraplegia

Syphilitic aortic aneurysm

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