For the problem that some parameters in system dynamics model are difficult to quantify, cloud model, which has the excellent characteristic of qualitative and quantitative transformation, is used in the determination of parameters of system dynamics model. Firstly, the system dynamics model revealing interactive development between the logistics industrial clusters and urbanisation is proposed. Secondly, the specific procedures of parameters calibration based on cloud model are given. Finally, a case study based on Shenyang economic zone is employed to verify the proposed model. According to the simulation results, some best suggestions on interactive development between logistics industrial clusters and urbanisation are put forward.