Elastomeric pad bearings are widely applied in short-to medium-span girder bridges in China, with the superstructure restrained by reinforced concrete (RC) shear keys in the transverse direction. Field investigations after 2008 Wenchuan earthquake reveal that bearing systems had suffered the most serious damage, such as span falling, bearing displaced, and shear key failure, while the piers and foundations underwent minor damage. As part of a major study on damage mechanism and displacement control method for short-to medium-span bridges suffered in Wenchuan earthquake, a 1:4 scale, two-span bridge model supported on elastomeric pad bearings were recently tested on shake tables at Tongji University, Shanghai. The bridge model was subjected to increasing levels of four seismic excitations possessing different spectralA c c e p t e d M a n u s c r i p t Downloaded by [RMIT University Library] at 04:19 30 June 20162 characteristics. Two restraint systems with and without the restraint of RC shear keys were tested. A comprehensive analytical modeling of the test systems was also performed using OpenSees. The experimental results confirmed that for the typical bridges on elastomeric pad bearings without RC shear keys, the sliding effect of the elastomeric pad bearings plays an important role in isolation of ground motions and, however, lead to lager bearing displacement that consequently increases the seismic risk of fall of span, especially under earthquakes that contain significant mid-period contents or velocity pulse components. It is suggested from the test results that RC shear keys should be elaborately designed in order to achieve a balance between isolation efficiency and bearing displacement. Good correlation between the analytical and the experimental data indicates that the analytical models for the bearing and RC shear key as well as other modeling assumptions were appropriate.