This paper proposes a new space-time multi-user receiver with decoupled interference cancellation and multi-user detection for wireless (mobile) communications. The proposed receiver, called a decoupled space-time multi-user detector (D-ST-MUD) utilizes spatial filtering for interference cancellation and maximum likelihood (ML) multi-user detection for joint demodulation of co-channel user signals. As opposed to classical multi-user receivers, the proposed receiver enjoys the nice property of being robust to cases where short-delayed paths of co-channel users are spatially correlated. Instead of being separated by the spatial filter, these short-delayed paths are passed to the ML multi-user detector that effectively combine and jointly demodulate the user signals. The main role of the spatial filter is to suppress long-delayed paths only. As a consequence, the D-ST-MUD receiver has the attractive characteristics of dealing with more signals than antenna-elements as well as being a low-complexity ML multi-user detector.