“…Nevertheless, even for expert engineers, determining the optimal operating strategy for WWTPs remains quite difficult and laborious given the complexity of the underlying biochemical phenomena, their interaction, and the large number of operating parameters to deal with [21]. In addition, the commonly used proportional-integral and proportional-integral-derivative controllers in the context of control in WWTPs cannot predict the problematic situations nor lead back the control process toward optimal conditions [20,[22][23][24]. Therefore, given the strengthening of stringent discharge standards and highly dynamic influent loadings with variable concentration of pollutants, it is very challenging to design, and then effectively implement, real-time optimal control strategies for the existing wastewater treatment processes [7].…”