Systematic Design of Medical Capsule Robots

Beccani, Marco; Tunc, Hakan; Taddese, Addisu Z.; Susilo, E.; Völgyesi, Péter; Lédeczi, Ákos; Valdastri, Pietro

doi:10.1109/mdat.2015.2459591

Cited by 16 publications

(17 citation statements)

References 17 publications

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“…As discussed in [7], the main purpose of our modular design environment is to accelerate the time-to-prototype for the early validation of design hypothesis in the field of MCRs. The time-to-prototype depends principally on the complexity of the hardware and software of the MCR as well as the skill-set and experience of the developer.…”

Section: Discussionmentioning

confidence: 99%

“…The base station [7] was used to exchange wireless data between the MCR and the user interface. In this particular application, the user might desire to change the delivered therapy schedule after the capsule has been ingested, thus the base station is the only way to interact with the DDC.…”

Section: Hardware Architecturementioning

confidence: 99%

“…In addition, setting up tool chains and the necessary software libraries for a specific target device is usually cumbersome. To alleviate these hardships, we have developed a web-based visual software design environment [7].…”

Section: Design Environment and Schedulermentioning

confidence: 99%

“…Therefore, MCR design and development requires significant skills and efforts in embedded systems, miniaturized electronics, packaging, debugging, and mechanical miniaturization of the device. Custom circuit boards and mechanical enclosures have to be engineered, which makes MCR development an expensive and time consuming process that is only accessible to a limited number of groups in the research community [7].…”

Section: Introductionmentioning

confidence: 99%

“…In our previous works, we presented our contributions towards the creation of an environment for the rapid design and development of MCRs [7,8,9]. The basic elements of the integrated design environment are shown in Fig.…”

Section: Introductionmentioning

confidence: 99%

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Component based design of a drug delivery capsule robot

Beccani

Aiello

Gkotsis

et al. 2016

Sensors and Actuators A: Physical

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Since the introduction of Wireless Capsule Endoscopy (WCE) researchers have started exploring the design space of Medical Capsule Robots (MCRs): embedded micro-systems that can operate autonomously within the human body and can diagnose, prevent, monitor, and cure diseases. Although the research in the area of MCRs is an active topic and has grown exponentially, current devices provide only limited functionalities because their design process is expensive and time consuming. To open this research field to a wider community and, at the same time, create better designs through advanced tool support, in our previous works we presented a design environment for the rapid development of MCRs. In this paper, this environment was adopted to design a Drug Delivery Capsule (DDC) based on a coil-magnetpiston mechanism. The force of the coil acting on the magnetic piston and the drug release profile were modeled and assessed on bench-top with a maximum relative error below 5%. Then, in vivo trials were performed to validate the DDC functionality with a scheduled drug release profile for a 5 hours and 24 minutes procedure. The resulting design environment template is available open source for further development of drug delivery applications as well as to serve as guideline in prototyping novel MCRs addressing other clinical needs.

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Section: Discussionmentioning

confidence: 99%

Section: Hardware Architecturementioning

confidence: 99%

Section: Design Environment and Schedulermentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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