The optical depth of aerosols plays a crucial role in scientific research and environmental policies, making it possible to understand the distribution and extent of aerosols in various regions of Brazil. The objective of this study is to evaluate the estimates of Aerosol Optical Depth (AOD) from the Copernicus Atmosphere Monitoring Service (CAMS) product in Brazil. The study covered the sites of Alta Floresta, Ji-Paraná, Rio Branco, Manaus, ATTO, São Paulo-EACH, São Paulo, Itajubá, Cuiabá, São Martinho, Petrolina and Campo Grande. Measured and estimated values were evaluated using Pearson correlation index "r", accuracy using Willmott index "d", Mean Squared Error, Mean Absolute Error and Percentage Bias. Results from the CAMS product showed good agreement with AOD measurements from the Aerosol Robotic Network. There was a strong correlation between the data, with Willmott index "d" values close to 1 and relatively low errors. However, significant differences were observed in some sites, such as Ji-Paraná, Rio Branco, Manaus and ATTO, where the CAMS tended to overestimate the AOD, while in Petrolina there was an underestimation. Variations in AOD occurred in various regions of Brazil over the years analyzed, with an increase during the dry season due to fires and human activities, and a reduction during the rainy months. The areas most affected were those close to the arc of deforestation in the Amazon. Aerosol concentrations have also been influenced by climatic factors, agricultural, industrial and urban activities in different regions of the country. This variability highlights the complexity of the natural and anthropogenic factors that affect air quality and emphasizes the importance of control and mitigation strategies for aerosol emissions. Therefore, the CAMS has demonstrated satisfactory performance in estimating the AOD in Brazil, providing valuable information on aerosol concentrations.