Systematic Lymphadenectomy Improves Survival in Patients with Advanced-Stage Primary Fallopian Tube Cancer

Prognostic factors of primary fallopian tube cancer in a single institute in Taiwan

“…Klein et al [23] reported that the median survival was 43 and 21 months in patients with and without lymph node dissection, respectively. Kim et al [24] also found that lymphadenectomy could improve overall survival and disease‐free survival in patients with advanced‐stage PFTC. Given that retroperitoneal lymph node metastasis indicates a poor prognosis and is associated with a nearly five‐fold increased risk of recurrence and a three‐fold increased risk of death, and given that optimal debulking surgery provided better chances of disease‐free survival and overall survival (> 90% decrease in the risks of recurrence/death), extensive retroperitoneal lymphadenectomy is highly recommended.…”

Primary Fallopian Tube Carcinoma

“…For patients with positive lymph node involvement, the means of OS and DFS have been reported to be significantly shorter than those of the patients with negative lymph node involvement. 31,32 In a retrospective multicenter study, lymphadenectomy has been demonstrated as an independent prognostic factor in OS analysis. 30 However, Klein et al compared 2 groups of patients with or without lymphadenectomy in primary treatment.…”

Para‐aortic lymphadenectomy for primary fallopian tube cancer

“…However, there is no consensus about the implications of extensive lymphadenectomy for PFTC. Lymph node involvement has significant value as a prognostic factor and influences disease-free survival and overall survival [9,10], and yet the therapeutic value of lymphadenectomy itself has not been clarified.…”