Systematic review and meta-analysis of the incidence and prevalence and 30-year trend of inflammatory bowel diseases in Asia: a study protocol

Safarpour, Ali Reza; Mehrabi, Manoosh; Keshtkar, Abbasali; Edjtehadi, Fardad; Lankarani, Kamran Bagheri

doi:10.1136/bmjopen-2019-031854

Cited by 9 publications

(6 citation statements)

References 41 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In recent decades, a similar pattern has also been observed among Asian countries, incidences for both UC and CD have risen rapidly in Asia, with CD having a steeper rise in more developed countries, resulting in a decrease in UC: CD ratio over time (5). The highest and lowest incidence rates were 3.2 and 0.06 for CD and 4.6 and 0.42 for UC per 100 000 person-years in East Asia (6). However, a recent study implicated measuring some oxidative stress parameters of both CD and UC patients, and in a research study shows that many cytokines were substantially upregulated in both CD and UC in contrast with Control group or the non-IBD (7,8).…”

Section: Introductionsupporting

confidence: 58%

Determination Total Creatine Kinase Activity and Creatine Kinase Isoenzymes Activities in Patients with Ulcerative Colitis and Crohn’s Disease under Infliximab Therapy

Al-timimi,

Al-Issa,

Alkhalidi

2021

Indian Journal of Forensic Medicine & Toxicology

View full text Add to dashboard Cite

Creatine kinase (CK) catalyzes the transfer of a phosphate group from creatine phosphate to adenosine diphosphate, and the CK has three isoenzymes CK-MM, CK-MB and CK-BB. Ulcerative colitis (UC) and Crohn's disease (CD) they are both conditions characterized by long life inflammation of the gastrointestinal system. The Purpose of this study was to determine the total CK activity and CK isoenzymes in patients with Crohn's Disease and Ulcerative Colitis under Infliximab therapy. For the UC patients, CD patients and controls the CK isoenzyme activities and total CK activity was measured, the three CK isoenzymes separate by suitable ion-exchanger small columns (DEAE-Sephadex A-50 exchanger). The results display Creatine kinase isoenzyme chromatograms of all studied groups (UC, CD patients and controls), with variable activities of (CK-BB) and (CK-MB) isoenzymes with noted an elevation of (CK-MM) isoenzyme activities and significantly elevation total CK activity in serum of patient groups after therapy when compared with before therapy patient groups.

show abstract

Section: Introductionsupporting

confidence: 58%

Determination Total Creatine Kinase Activity and Creatine Kinase Isoenzymes Activities in Patients with Ulcerative Colitis and Crohn’s Disease under Infliximab Therapy

Al-timimi,

Al-Issa,

Alkhalidi

2021

Indian Journal of Forensic Medicine & Toxicology

View full text Add to dashboard Cite

show abstract

“…Heterogeneity values of 0%-40%, 30%-60%, 50%-90%, and 75%-100% will be considered as ‘perhaps not important’, ‘moderate heterogeneity’, ‘substantial heterogeneity’, and ‘considerable heterogeneity’, respectively. For the Q-test, P < 0.05 will be considered statistically significant ( 32 ).…”

Section: Methodsmentioning

confidence: 99%

Aminophylline for Prevention and/or Treatment of Post-Dural Puncture Headache: A Systematic Review and Meta-Analysis Study Protocol

et al. 2021

Self Cite

View full text Add to dashboard Cite

Objectives: Post-dural Puncture Headache (PDPH) is prevalent among individuals undergoing lumbar punctures. The non-invasive effect of some drugs, such as aminophylline on PDPH has been investigated in several clinical studies. As there is no comprehensive systematic review and meta-analysis about the preventive and therapeutic effects of aminophylline on PDPH in the literature, the clinical effectiveness of this drug on the prevention and/or treatment of PDPH will be assessed in this study. Methods: PubMed/MEDLINE, Embase, WoS (Clarivate Analytics), the Cochrane Central Register of Controlled Trials (CENTRAL), CINAHL Complete, Scopus, and Google Scholar as electronic databases will be precisely searched for clinical studies that assessed the effect of aminophylline on PDPH. Studies between 01-01-1980 and 30-06-2020 will be evaluated in this study, and there will not be any language restrictions. Contradictions between the reviewers within any phase of the study (screening, selecting, quality assessment, and data extraction) will be resolved by consensus; in case of unsolved disagreements, a third reviewer will eventually decide. The combination method will be applied according to the methodological resemblance in the selected articles using the Random Effect Model or the Fixed Effect Model. Also, for the included articles, forest plots will be drawn. For assessing statistical heterogeneity, the I2 statistic and the Q-statistic test will be applied. In addition, funnel plots will be used for assessing non-significant study effects and potential reporting bias. Furthermore, Egger’s and Begg’s tests will be done, and publication bias will be indicated by significant findings (P < 0.05). Conclusions: It is expected that the results of this study will be of benefit to researchers and clinicians for managing PDPH, and will be reported in conferences and publications.

show abstract

“…In the case, if non-English studies will be selected for inclusion in the review, Google Translate will be used to translate into English. [18][19][20] Moreover, to avoid errors, the studies will be rechecked by official translators and then assessed for the final selection. Students from the Peking University will also provide support in translating non-English articles.…”

Section: Study Selection and Data Extractionmentioning

confidence: 99%

Prevalence of acute liver injury and hypertransaminemia in patients with COVID-19: a protocol for a systematic review

Xu²,

Yang

et al. 2020

BMJ Open

View full text Add to dashboard Cite

IntroductionCOVID-19 has spread rapidly in China and around the world. Published studies have revealed that some patients with COVID-19 had abnormal liver function in laboratory tests. However, the results were inconsistent and the analysis of epidemiological data stratified by the severity of COVID-19 was not available in previous meta-analyses. Furthermore, these meta-analyses were suspected of overestimating the incidence of liver injury in patients with COVID-19 because some studies considered transaminase elevation as liver injury, which might partially result from cardiac and muscle injury. This systematic review aims to enrol published literatures related to COVID-19 without language restriction, analyse the data based on the severity of the COVID-19 and explore the impact of varied definitions of liver injury on the incidence of liver injury.Methods and analysisWe have conducted a preliminary search on PubMed and Excerpta Medica Database on 13 April 2020, for the studies published after December 2019 on the prevalence of acute liver injury and hypertransaminemia in patients with COVID-19. Two reviewers will independently screen studies, extract data and assess the risk of bias. We will estimate the pooled incidence of hypertransaminemia and acute liver injury in patients with COVID-19 by using the random-effects model. The I² test will be used to identify the extent of heterogeneity. Publication bias will be assessed by funnel plot and performing the Begg’s and Egger’s test if adequate studies are available. We will perform a risk of bias assessment using the Joanna Briggs Institute’s critical appraisal checklist.Ethics and disseminationSince this study will be based on the published data, it does not require ethical approval. The final results of this study will be published in a peer-reviewed journal.PROSPERO registration numberCRD42020179462.

show abstract

Systematic review and meta-analysis of the incidence and prevalence and 30-year trend of inflammatory bowel diseases in Asia: a study protocol

Cited by 9 publications

References 41 publications

Determination Total Creatine Kinase Activity and Creatine Kinase Isoenzymes Activities in Patients with Ulcerative Colitis and Crohn’s Disease under Infliximab Therapy

Determination Total Creatine Kinase Activity and Creatine Kinase Isoenzymes Activities in Patients with Ulcerative Colitis and Crohn’s Disease under Infliximab Therapy

Aminophylline for Prevention and/or Treatment of Post-Dural Puncture Headache: A Systematic Review and Meta-Analysis Study Protocol

Prevalence of acute liver injury and hypertransaminemia in patients with COVID-19: a protocol for a systematic review

Contact Info

Product

Resources

About