Systematic review and validation of prediction rules for identifying children with serious infections in emergency departments and urgent-access primary care.

Abstract

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Comparison of the Eosinophil Count to C –reactive protein, Leukocyte Count, and Neutrophil Count for the detection of bacterial infection in ill-appearing children with fever admitted to the Emergency Department

“…(18,19) We found that a low blood eosinophil count (≤ 50 cells/mm 3 ) is similar to a high CRP level (≥1.22 mg/dL) and a high neutrophil count (>5100 cells/mm 3 ) for predicting bacterial infection in the pediatric emergency department. However, none of them had sufficient discriminatory power.…”

“…C-reactive protein (CRP) and the leukocyte and neutrophil counts are the acute-phase reactants used most widely in children admitted to the emergency department with a high fever. (1)(2)(3) In the last 20 years, procalcitonin has been identified as a promising bacterial infection marker in children with fever. Also, CD 15s as a neutrophil surface molecule was reported a potentially valuable biomarker in infants with severe bacterial infection.…”

Reliability of Telemedicine in the Assessment of Seriously Ill Children

“…13 The YOS has been validated in follow-up studies. 14,16 A convenience sample of children aged 2 months to 18 years presenting with respiratory symptoms (eg, cough, dyspnea, wheezing) were evaluated by using the Respiratory Observation Checklist (Fig 2). This tool, developed specifically for the present study by the authors, is a checklist of common observational signs of respiratory distress.…”

“…However, previous studies evaluating the role of observation in assessing febrile children and children in respiratory distress have validated observation as both predictive and reliable in identifying underlying serious illness. [13][14][15][16] The purpose of the present study was to determine the interobserver reliability of telemedicine observations, compared with bedside observations, in assessing febrile children and children in respiratory distress.…”

What’s New in the Recognition and Management of Septic Shock in Children: Dos and Don'ts

“…While recognition of septic shock may be relatively straightforward in the context of an intensive care unit that deals with many such patients, it is much more challenging to ensure that early signs of septic shock are recognized in children initially presenting to healthcare services where such problems are much less frequent [21,22]. Studies of meningococcal disease suggest that while the ''full-blown'' picture may be easy to recognize, the clinical features in the early phase of the disease may be very non-specific and subtle [23].…”