Systematic review of epidemiology, presentation, and management of Meckel's diverticulum in the 21st century

Hansen, Carl-Christian; Søreide, Kjetil

doi:10.1097/md.0000000000012154

Cited by 213 publications

(368 citation statements)

References 57 publications

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“…Although it is universally accepted that a complicated MD must be removed, the resection of an incidentally discovered uncomplicated MD remains controversial . Zani et al reported a complication rate of 1.3% in incidentally discovered uncomplicated MDs left in situ compared to a complication rate of 5.3% after resection and opposed resection .…”

Section: Discussionmentioning

confidence: 99%

“…Analogous studies opposed the resection of an incidentally discovered uncomplicated MD . Other studies reported a 1.2–2% complication risk after MD resection compared with a lifetime morbidity risk 6.4–7% and recommended resection of all MDs encountered . The reported association of MD with intestinal cancer in adulthood impelled the tendency towards resection …”

Section: Discussionmentioning

confidence: 99%

“…after the first step with the exclusion of the complicated MDs as shown in Figs ,). (iv) Although its importance is well recognized, heterotopy may not be considered the only factor that determines lifetime MD‐related morbidity …”

Section: Discussionmentioning

confidence: 99%

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Predictive model of heterotopy in Meckel's diverticulum in children

Sinopidis

Fouzas

Kambouri

et al. 2019

ANZ Journal of Surgery

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Background:The presence of heterotopic tissue in Meckel's diverticulum (MD) increases the incidence of future complications. Based on this concept, this study aimed to detect clinical and morphological parameters able to predict the probability of heterotopy in incidentally discovered uncomplicated MD and to develop a risk-based classification tool. Methods: The clinical records of 146 patients who underwent MD resection were reviewed. MD complications (bleeding, inflammation, perforation or involvement in pathological processes such as intussusception) and MD dimensions (width, length and the product width × length) were evaluated in association with heterotopy. Regression analysis was used to explore the discrete effect of clinically relevant parameters, which were subsequently combined in a Classification and Regression Tree. Results: The probability of heterotopy was higher in complicated MDs. The width of the base of the MD and the product width × length were also significant predictors of heterotopy. A stepwise combination (Classification and Regression Tree model) of (i) uncomplicated macroscopic presentation, (ii) width <2.5 cm, (iii) age <10 years and (iv) product width × length <4 cm 2 resulted in a null probability of heterotopy in our study group. Conclusion: The combination of MD-related clinical and morphological parameters using advanced statistical tools may assist in estimating the probability of heterotopy. This may be applied in incidentally discovered uncomplicated MDs during abdominal surgery for other morbidities. Prospective studies are required to confirm our findings and test the practical usefulness of the classification tool developed here. © 2019 Royal Australasian College of Surgeons ANZ J Surg 89 (2019) E241-E245ANZJSurg.com

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Predictive model of heterotopy in Meckel's diverticulum in children

Sinopidis

Fouzas

Kambouri

et al. 2019

ANZ Journal of Surgery

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“…Meckel's diverticulum represents a remnant of the omphalomesenteric duct, which results from the failure of the duct to obliterate during the 5 th -7 th gestational week [1]. It is identified in 0.3-2.9% of the general population, whereas complications develop in 4.2-9.0% of the affected patients [2,3]. Tc 99m scintigraphy constitutes the most widely used imaging modality, with sensitivity and specificity of 80-100% and 50-100%, respectively [3].…”

mentioning

confidence: 99%

“…It is identified in 0.3-2.9% of the general population, whereas complications develop in 4.2-9.0% of the affected patients [2,3]. Tc 99m scintigraphy constitutes the most widely used imaging modality, with sensitivity and specificity of 80-100% and 50-100%, respectively [3].…”

mentioning

confidence: 99%