Systematic review of perioperative use of immunosuppressive agents in patients undergoing bariatric surgery

Kassel, Lynn; Hutton, Anastasia; Zumach, Gregory; Rand, Joel Eugene

doi:10.1016/j.soard.2019.10.002

Cited by 4 publications

(3 citation statements)

References 52 publications

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“…This observation is in line with the literature [5,35,43,44]. Ramanujam et al proposes that this finding might rather be due to the comorbidities of diabetics [4,6,[45][46][47]. However, Baltzis et al describe biological mechanisms of wound healing that may be affected by diabetes mellitus [44].…”

Section: Discussionsupporting

confidence: 85%

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Conditions Associated with Wound Healing Complications After Adjuvant Radiotherapy in Patients with Non-Melanoma Skin Cancer: A Retrospective Analysis

Hobelsberger¹,

Lohaus²,

Löck³

et al. 2022

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In the treatment of highly malignant skin tumors postoperative radiotherapy may be indicated after wound closure.In the University Hospital Carl Gustav Carus Dresden, Germany, a retrospective study of 75 patients, who received postoperative radiotherapy after wound closure, was conducted. In all 75 patients (56 male, 19 female), radical doses of irradiation (40-70 Gy in 20-35 fractions) were administered. The median time interval between surgery and radiation therapy was 7 weeks (range 3-48 weeks). The incidence of wound healing complications (WHCs) increased after radiotherapy (p<0.001). Univariable analysis showed that WHCs were associated with immunosuppression (p=0.002), split thickness skin graft (p=0.007) lymphoma or leukemia (p=0.032) and diabetes mellitus (p=0.046). Multivariable logistic regression showed that independent risk factors for WHCs were split thickness skin transplantation (odds ratio: 3.85, 95% confidence interval (CI): 1.13-13.1, p=0.031) and immunosuppression (odds ratio: 4.69, 95% CI: 1.18-18.7, p=0.029). The authors observed no association between surgical site infections and WHCs (p=1.0). Univariable analysis showed that SSIs were associated with leukemia or lymphoma (p=0.019). Together, the results show an increased incidence of WHCs after radiotherapy. Other conditions associated with WHCs were leukemia or lymphoma and diabetes mellitus. Immunosuppression and split thickness skin transplantation were independent risk factors for WHCs.

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Section: Discussionsupporting

confidence: 85%

“…Individual studies reported no increased occurrence of WHC like necrosis in diabetics [1,4]. The risk of WHC in a patient with diabetes mellitus might depend on additional comorbidities and on how well the diabetes is controlled [4,6,[44][45][46][47].…”

Section: Discussionmentioning

confidence: 99%

Conditions Associated with Wound Healing Complications After Adjuvant Radiotherapy in Patients with Non-Melanoma Skin Cancer: A Retrospective Analysis

Hobelsberger¹,

Lohaus²,

Löck³

et al. 2022

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“…7 Other literature studying its effects on bone and wound healing show that it is likely to be safe to operate on patients taking low doses. 8,9 Inflamed, crusted mucosa is a warning sign that there may be some active disease. These patients often have sinus disease and this may need to be treated also.…”

Section: Workupmentioning

confidence: 99%

Correction of the Saddle Nose Deformity

Hamilton

2020

Facial plast Surg

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Saddle nose deformities are among the most challenging problems in rhinoplasty. These patients have often had previous surgery and may have complicated medical histories. Reconstructing the septum is a necessary prerequisite to correcting the contour of the nose. With proper planning and thoughtful execution, patients suffering from disfiguring saddle noses can be safely operated on—even those with vasculitic diseases.

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Sleeve Gastrectomy in Immunocompromised Patients

Andalib

2021

Laparoscopic Sleeve Gastrectomy

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Systematic review of perioperative use of immunosuppressive agents in patients undergoing bariatric surgery

Cited by 4 publications

References 52 publications

Conditions Associated with Wound Healing Complications After Adjuvant Radiotherapy in Patients with Non-Melanoma Skin Cancer: A Retrospective Analysis

Conditions Associated with Wound Healing Complications After Adjuvant Radiotherapy in Patients with Non-Melanoma Skin Cancer: A Retrospective Analysis

Correction of the Saddle Nose Deformity

Sleeve Gastrectomy in Immunocompromised Patients

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