Systematic Review of Studies Comparing the Anti-Caries Efficacy of Children’s Toothpaste Containing 600 ppm of Fluoride or Less with High Fluoride Toothpastes of 1,000 ppm or Above

Ammari, Amera B; Bloch‐Zupan, Agnès; Ashley, Paul

doi:10.1159/000069022

Cited by 111 publications

(86 citation statements)

References 14 publications

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“…Ammari et al [1] reported about randomized controlled trials comparing low fluoride toothpastes containing 600 ppm F or less with toothpastes containing 1000 ppm or more in children and adults that 250 ppm fluoride dentifrices are not as effective in caries prevention as dentifrices containing 1000 ppm fluoride. The results of our study are in accordance with these clinical studies.…”

Section: Discussionmentioning

confidence: 99%

Remineralization of initial carious lesions in deciduous enamel after application of dentifrices of different fluoride concentrations

et al. 2009

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The aim of the present study was to evaluate the remineralization potential of five dentifrices with different fluoride concentrations. Initial caries lesions were created in 72 cylindrical enamel blocks from deciduous teeth. The specimens were randomly distributed among six experimental groups corresponding to six experimental periods. Each of the six volunteers carried two deciduous enamel specimens fixed in an intraoral appliance for a period of 4 weeks. They brushed their teeth and the enamel blocks at least two times a day with dentifrices containing 0 ppm (period 1), 250 ppm (period 2), and 500 ppm fluoride (period 3), respectively. A second group of volunteers (n = 6) used dentifrices with a fluoride content of 0 ppm (period 4), 1,000 ppm (period 5), or 1,500 ppm (period 6). At the end of the respective period, the mineral content was determined by transversal microradiography (TMR). The use of dentifrices containing 500 ppm fluoride (38% MR), 1,000 ppm fluoride (42% MR), and 1,500 ppm fluoride (42% MR) resulted in a statistically significant higher mineral recovery compared to the control group (0 ppm fluoride). Mineral recovery was similar after use of dentifrices containing 0 and 250 ppm fluoride (24%; 25%). It is concluded that it is possible to remineralize initial carious lesions in deciduous enamel in a similar way as it has been described for enamel of permanent teeth. Abstract:The aim of the present study was to evaluate the remineralization potential of 5 dentifrices with different fluoride concentrations. Initial caries lesions were created in 72 cylindrical enamel blocks from deciduous teeth. The specimens were randomly distributed among 6 experimental groups corresponding to 6 experimental periods. Each 6 volunteers carried 2 deciduous enamel specimens fixed in an intraoral appliance for a period of 4 weeks. They brushed their teeth and the enamel blocks at least 2 times a day with dentifrices containing 0 ppm (period 1); 250 ppm (period 2), and 500 ppm fluoride (period 3), respectively. A second group of volunteers (n = 6) used dentifrices with a fluoride content of 0 ppm (period 4), 1000 ppm (period 5) or 1500 ppm (period 6). At the end of the respective period the mineral content was determined by transversal microradiography (TMR). The use of dentifrices containing 500 ppm fluoride (38% MR), 1000 ppm fluoride (42%MR ), and 1500 ppm fluoride (42% MR) resulted in a statistically significant higher mineral recovery compared to the control group (0 ppm fluoride). Mineral recovery was similar after use of dentifrices containing 0 and 250 ppm fluoride (24%; 25%). It is concluded that it is possible to remineralize initial carious lesions in deciduous enamel in a similar way as it has been described for enamel of permanent teeth.

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Section: Discussionmentioning

confidence: 99%

Remineralization of initial carious lesions in deciduous enamel after application of dentifrices of different fluoride concentrations

et al. 2009

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“…500 ppm F), a significant number of studies and systematic reviews of the literature have been published in the last few years. In a systematic review published in 2003, Ammari et al 29 concluded that more studies were necessary to address the effect of 500 ppm F toothpastes, and that lower concentrations (e.g. 250 ppm F) were clearly not as effective as the conventional toothpastes to control caries.…”

Section: Individual Methods Of Fluoride Usementioning

confidence: 99%

Fluoride: its role in dentistry

Tenuta¹,

2010

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In spite of decades of research on fluoride and the recognition of its role as the cornerstone of dental caries reduction in the last fifty years, questions still arise on its use at community, self-applied and professional application levels. Which method of fluoride delivery should be used? How and when should it be used? How can its benefits be maximized and still reduce the risks associated with its use? These are only some of the challenging questions facing us daily. The aim of this paper is to present scientific background to understand the importance of each method of fluoride use considering the current caries epidemiological scenario, and to discuss how individual or combined methods can be used based on the best evidence available.

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“…17 Low fluoride toothpastes, containing less than 600 ppm F, are available for young children in the UK. A recent systematic review 18 concluded that toothpastes containing 250 ppm F were not as effective at preventing caries in the permanent dentition as toothpastes containing 1000 ppm F or more (Type 1). Clinical trials in pre-school children (Type 2) comparing 550 ppm F with 1055 ppm F 19 and 440 ppm F with 1450 ppm F 20 have demonstrated that toothpastes containing the lower concentrations of fluoride provide less protection than those containing higher concentrations.…”

Section: Fluoride Concentrationmentioning

confidence: 99%