Systematic Review of the Effect of Aging on Health Costs

The Contribution of Genetic Testing in Optimizing Therapy for Patients with Recurrent Depressive Disorder

“…MDD is a complex disorder that has been considered for more than two decades to have a background of increased heritability, reaching as high as 37% according to the estimates of two twin studies [ 33 , 34 , 35 , 36 ]. Despite strong evidence for a genetic component, identifying the specific gene variants responsible for the development of this disorder has always constituted a major challenge.…”

“…Over time, the hypothesis of a common genetic background has been tested as a potential basis for this relationship. A previous family study by Hettema et al [ 36 ] debated evidence concerning the co-occurrence of anxiety and MDD, while twin studies indicate shared genetic risk factors that could potentially explain these comorbidities [ 32 , 33 , 36 ]. Therefore, studying the molecular genetics of these pathologies can potentially provide support for specific genetic loci that could influence individuals’ susceptibility to developing a spectrum of depressive and/or anxious symptoms [ 37 , 38 ].…”

Divergences in Antiviral Therapy for Diabetic Patients with COVID-19

“…The present study suggests that molnupiravir could be a promising option in the treatment of hospitalized adult COVID-19 patients with diabetes, with positive results in terms of reducing the risk of severe complications, controlling inflammation, and tolerability. Reducing the length of hospitalization leads to a decrease in associated costs, especially for individuals over the age of 65 [64]. Considering the multitude of complications that COVID-19 can induce in both the immediate and extended periods, promptly halting viral replication during the illness is crucial for restoring the body's balance.…”