Systematic review of the effect of coenzyme Q10 on antioxidant capacity while focused on evaluation of claims for health functional food

Kim, Ji Yeon; Jeong, Sang‐Ho; Paek, Ju Eun; Kim, Joohee; Kwak, Jin Sook; Lee, Yoon Jung; Kang, Tae Seok; Kwon, Oran

doi:10.4163/jnh.2013.46.3.218

Cited by 7 publications

(1 citation statement)

References 39 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This study examined whether coenzyme Q10, an antioxidant supplement, could improve insulin resistance in people with prediabetes. Currently, the Korean Food and Drug Administration (KFDA) guidelines recommend a daily intake of 100 mg of coenzyme Q10, with a maximum daily intake of 200 mg [ 15 ]. Following a study by Raygan et al [ 13 ], we determined that a daily dose of 200 mg of coenzyme Q10 for a treatment duration of 8 weeks would comply with the KFDA guidelines.…”

Section: Discussionmentioning

confidence: 99%

Effect of Coenzyme Q₁₀ on Insulin Resistance in Korean Patients with Prediabetes: A Pilot Single-Center, Randomized, Double-Blind, Placebo-Controlled Study

Yoo

Yum

2018

BioMed Research International

View full text Add to dashboard Cite

Introduction This study aimed to examine whether administration of coenzyme Q10, an antioxidant, improves insulin resistance in patients with prediabetes. The study design was a pilot single-center, randomized, double-blind, placebo-controlled trial. Methods This pilot single-center, randomized, double-blind, placebo-controlled trial included a total of 80 adults (aged ≥20 years) with impaired glucose tolerance. After the initial screening visit, subjects were assigned to either the experimental (n = 40) or placebo (n = 40) group via simple randomization. Insulin resistance was represented as the insulin resistance index estimated by homeostasis model assessment (HOMA-IR). Results After the 8-week treatment period, the coenzyme group exhibited a significant decrease in the HOMA-IR (P < .001). The free oxygen radical and coenzyme Q10 concentrations were found to correlate significantly (P < .001). However, no significant changes in fasting blood glucose, insulin, and glycated hemoglobin levels were observed in either group. Additionally, no adverse events occurred in either group. Conclusion Patients with prediabetes who were administered coenzyme Q10 showed a significant reduction in HOMA-IR values. Therefore, administration of coenzyme Q10 in patients with impaired glucose tolerance may slow the progression from prediabetes to overt diabetes.

show abstract

Section: Discussionmentioning

confidence: 99%

Effect of Coenzyme Q₁₀ on Insulin Resistance in Korean Patients with Prediabetes: A Pilot Single-Center, Randomized, Double-Blind, Placebo-Controlled Study

Yoo

Yum

2018

BioMed Research International

View full text Add to dashboard Cite

show abstract

Skin health functionality evaluation of collagen peptide with the application of meta analytical approach

Yoon,

Lee,

Jung

2024

Journal of Functional Foods

View full text Add to dashboard Cite

Effect of Supercritical Carbon Dioxide on Physicochemical Properties of Freeze-Dried Bovine Liver

Kim¹,

Woo²,

Kang³

et al. 2015

J. Agirc. Life Sci.

View full text Add to dashboard Cite

Systematic review of the effect of coenzyme Q10 on antioxidant capacity while focused on evaluation of claims for health functional food

Cited by 7 publications

References 39 publications

Effect of Coenzyme Q₁₀ on Insulin Resistance in Korean Patients with Prediabetes: A Pilot Single-Center, Randomized, Double-Blind, Placebo-Controlled Study

Effect of Coenzyme Q₁₀ on Insulin Resistance in Korean Patients with Prediabetes: A Pilot Single-Center, Randomized, Double-Blind, Placebo-Controlled Study

Skin health functionality evaluation of collagen peptide with the application of meta analytical approach

Effect of Supercritical Carbon Dioxide on Physicochemical Properties of Freeze-Dried Bovine Liver

Contact Info

Product

Resources

About

Systematic review of the effect of coenzyme Q10 on antioxidant capacity while focused on evaluation of claims for health functional food

Cited by 7 publications

References 39 publications

Effect of Coenzyme Q10 on Insulin Resistance in Korean Patients with Prediabetes: A Pilot Single-Center, Randomized, Double-Blind, Placebo-Controlled Study

Effect of Coenzyme Q10 on Insulin Resistance in Korean Patients with Prediabetes: A Pilot Single-Center, Randomized, Double-Blind, Placebo-Controlled Study

Skin health functionality evaluation of collagen peptide with the application of meta analytical approach

Effect of Supercritical Carbon Dioxide on Physicochemical Properties of Freeze-Dried Bovine Liver

Contact Info

Product

Resources

About

Effect of Coenzyme Q₁₀ on Insulin Resistance in Korean Patients with Prediabetes: A Pilot Single-Center, Randomized, Double-Blind, Placebo-Controlled Study

Effect of Coenzyme Q₁₀ on Insulin Resistance in Korean Patients with Prediabetes: A Pilot Single-Center, Randomized, Double-Blind, Placebo-Controlled Study