2020
DOI: 10.1016/j.ijid.2019.10.025
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Systematic review on respiratory syncytial virus epidemiology in adults and the elderly in Latin America

Abstract: Results: Eighteen studies were included. Percentages of RSV detection varied highly across included studies for adult subjects with respiratory infections (0% to 77.9%), influenza-like illness (1.0% to 16.4%) and community-acquired pneumonia (1.3% to 13.5%). Considerable percentages of hospitalization were reported for RSV-infected adults with influenza-like illness (40.9% and 69.9%) and community-acquired pneumonia (91.7%).

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Cited by 36 publications
(37 citation statements)
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“…RSV-related morbidity seems to be underestimated in other age groups than the pediatric age group; however, awareness on the impact of RSV in adults is increasing, and estimates report at least 10% of pneumonia cases in adults to be RSV-related [ 6 , 7 ]. Efforts towards RSV prevention have resulted in passive immunoprophylaxis with monoclonal antibodies administered to high-risk patients, while clinical trials on possible vaccines are still being conducted with no product licensed to date [ 8 , 9 ].…”
Section: Introductionmentioning
confidence: 99%
“…RSV-related morbidity seems to be underestimated in other age groups than the pediatric age group; however, awareness on the impact of RSV in adults is increasing, and estimates report at least 10% of pneumonia cases in adults to be RSV-related [ 6 , 7 ]. Efforts towards RSV prevention have resulted in passive immunoprophylaxis with monoclonal antibodies administered to high-risk patients, while clinical trials on possible vaccines are still being conducted with no product licensed to date [ 8 , 9 ].…”
Section: Introductionmentioning
confidence: 99%
“…RSV is commonly responsible for bronchiolitis in children, whereas in adults it is associated with influenza-like illness (ILI) or acute respiratory infections (ARIs) including pneumonia. RSV represents an underestimated clinical burden in adults, being the causative agent of 10.6%–13.5% of community pneumonia depending on whether patients are ambulatory or hospitalized [ 2 , 3 ]. Recent reports show that in hospitalized patients with RSV-ARI, intensive care unit (ICU) admission was necessary in 15%–16.8% of cases [ 4 , 5 ] and mortality ranged from 8% (in-hospital mortality) [ 5 ] to 11.9% at 60 days [ 6 ], which is comparable to that associated with influenza.…”
mentioning
confidence: 99%
“…At the same, as this new virus, is a concern for the world (at least it has already had a global economic impact), Latin America and even Colombia, among other regions and countries, Colombia faces an ongoing epidemic of dengue with over 130,000 cases, 1% of them severe, including more than 100 associated-deaths. When considering respiratory tract infections, multiple infectious agents are actively circulating, and will be increasing in the next few months in the region, including, those under surveillance, such as Influenza A (including AH1N1), Influenza B, human metapneumovirus, respiratory syncytial virus, adenovirus, parainfluenza 1, 2, 3 and 4, rhinovirus, bocavirus and enterovirus, among others [38][39][40] .…”
Section: Treatment and Preventionmentioning
confidence: 99%