Systematic Review With Network Meta-Analysis

Abstract

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Systematic Review and Network Meta-Analysis of Randomized Controlled Trials

“… 30 – 31 Detail information of Bayesian methods can be seen in our previous published network meta-analyses. 32 – 38 The pooled ORs from the network meta-analysis were compared with corresponding ORs from pair-wise random-effects meta-analysis of direct comparisons to assess whether there was inconsistency between direct and indirect comparisons. We assessed the probability that each treatment was the most effective therapy, the second best, and so on, by counting the proportion of simulations in which each treatment had the smallest ORs, the second smallest, and so on.…”

Network Meta-Analysis of Randomized Controlled Trials

“… 19 A multiple-treatment meta-analysis was performed according to the methods that we had previously described. 20 , 21 …”

A network meta-analysis of the efficacy and side effects of udca-based therapies for primary sclerosing cholangitis

“…It accounts for multiple comparisons within a trial when there are more than 2 treatment groups [ 42 – 43 ]. As we had described in our previous published network meta-analysis [ 44 – 47 ], analysis was based on non-informative priors for relative-effect parameters (flat normal with mean of 0 and precision of 0.001) and between-study SD (a flat uniform distribution between 0 and 2). Convergence and lack of autocorrelation were checked and confirmed after a 5000-simulation burn-in phase without any thinning and using 4 chains with different initial values.…”