The discovery of anomalies in the cosmic microwave background (CMB) indicates large-scale anisotropies, non-Gaussian distributions, and anomalous alignments of the quadrupole and octupole modes of the anisotropy with each other and with both the ecliptic and equinoxes. Further analysis indicates that the statistical anisotropy and non-Gaussian temperature°u ctuations are mainly due to long-range correlations. However, the source of the large-scale correlation and the cause of the anomalous alignment in CMB remains unknown. In this work, we show a new development in string theory, the universal wave function interpretation of string theory (UWFIST) indicates the existence of large-scale quantum vibrations. These largescale quantum vibrations can cause the large-scale correlation and anomalous alignment observed in the background¯eld. They can explain the observed large-scale anisotropies, non-Gaussian distributions, and anomalous alignments of the quadrupole and octupole modes in the microwave background.Keywords: Dark energy; anomalies in cosmic microwave background; string theory; large-scale anisotropies; anomalous alignments of the quadrupole and octupole modes of the anisotropy; universal wave function interpretation of string theory.