2019
DOI: 10.1016/j.annemergmed.2018.02.011
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Systemic Antibiotics for the Treatment of Skin and Soft Tissue Abscesses: A Systematic Review and Meta-Analysis

Abstract: The use of systemic antibiotics for skin and soft tissue abscesses after incision and drainage resulted in an increased rate of clinical cure. Providers should consider the use of antibiotics while balancing the risk of adverse events.

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Cited by 40 publications
(22 citation statements)
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“…Recent studies differ from ours in that they primarily focused on management of uncomplicated SSTI with I&D with or without the addition of oral antibiotics. 11,12,16 Talan et al 11 found that in patients with abscesses with a median length of 2.5 cm and depth of 1.5 cm who were treated with oral trimethoprim-sulfamethoxazole in conjunction with an I&D procedure had a higher cure rate when compared to patients who received an I&D procedure and placebo.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…Recent studies differ from ours in that they primarily focused on management of uncomplicated SSTI with I&D with or without the addition of oral antibiotics. 11,12,16 Talan et al 11 found that in patients with abscesses with a median length of 2.5 cm and depth of 1.5 cm who were treated with oral trimethoprim-sulfamethoxazole in conjunction with an I&D procedure had a higher cure rate when compared to patients who received an I&D procedure and placebo.…”
Section: Discussionmentioning
confidence: 99%
“…12 found that in patients with a skin abscess less than or equal to 5cm in diameter treated with oral antibiotics in combination with I&D had improved shortterm outcomes compared to those patients treated with I&D alone. A systematic review and meta-analysis by Gottlieb et al, 16 which included the two previously mentioned studies, found that the addition of antibiotics to a drainage procedure improved clinical cure in patients with a SSTI. In all of these studies all patients with an abscess underwent a drainage procedure.…”
Section: Discussionmentioning
confidence: 99%
“…Only 8% of included reviews (n=3) [22,43,54] provided the explanations for individual changes in the published full text and thus were considered to improve the reporting quality. Inclusion of the terms "systematic reviews" and "Meta-analysis" in review title [33] [43] [49] Exclusion of the terms "systematic reviews" and 'Meta-analysis" from review title [40] [46] The key information (PICO) about the scope of the reviews was provided [ Deleting the principal summary measures (risk ratio, difference in means, etc. )/the methods of handling data and combining results of studies (including measures of consistency for each meta-analysis)/the assessment of risk of bias that may affect the…”
Section: Categories and Impact Of Changes In Each Sectionmentioning
confidence: 99%
“…Figure 1 <p><em>Categories and impact of changes in each review</em></p> <p>All of the systematic reviews included in this study (n=39) have undergone some changes, pertaining to a total of 50 change categories (in Table 1). The most rigorous systematic review [50] involved four categories of changes, and the most varied systematic reviews [33] involved 14 categories of changes. The changes in 70% systematic reviews (n=27) have improved the quality as a whole (the number of improving being greater than the number of reducing and unclear).…”
Section: Availability Of Data and Materialsmentioning
confidence: 99%
“…All of the systematic reviews included in this study have undergone some changes compared to their protocols. A minimally rigorous systematic review [50] involved four categories of changes, and the most varied systematic reviews [33] involved 14 categories of changes. The changes in 77% systematic reviews (n = 30) have improved the quality as a whole (the number of improving being greater than the number of reducing and unclear).…”
Section: The Distribution Of Different Impact For Changes In Each Reviewmentioning
confidence: 99%