Systemic bone marker expression induced by grey and white mineral trioxide aggregate in normal and diabetic conditions

Queiroz, Índia Olinta de Azevedo; Mello, Wagner Garcez de; Martins, Christine Men; Dal‐Fabbro, Renan; Narciso, Luı́s; Massunari, Loiane; Cintra, Luciano Tavares Ângelo; Ervolino, Edílson; Gomes‐Filho, João Eduardo

doi:10.1111/iej.12900

Cited by 9 publications

(10 citation statements)

References 61 publications

(134 reference statements)

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“…In addiction, cytokines production and inflammatory response were not upregulated in hyperglycemic animals; however, a decrease in the calcium deposition was observed in presence of WMTA, suggesting a delay in the mineralization process [165]. These results are supported by a previous study that found in diabetic conditions an inhibitory effect on MTAinduced differentiation of OCN-and OPN-positive cells was detected [173].…”

Section: Impact Of Systemic Disorders On Biomineralization Of Endodon...supporting

confidence: 82%

Evolution of endodontic medicine: a critical narrative review of the interrelationship between endodontics and systemic pathological conditions

et al. 2021

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Endodontics has gained emphasis in the scientific community in recent years due to the increase in clinical and in animal models studies focused on endodontic medicine, which aims to evaluate the interrelationship between systemic and periapical tissues pathological conditions. These studies have shown that systemic changes can boost the pathogenesis of endodontic infection, favoring its development and progression. A contrary relationship is reported in numerous studies that affirm the potential of endodontic infection to trigger systemic damage and may lead to the worsening of pre-existing pathologies. Recently, the potential of filling materials to develop systemic changes such as neurological alterations had been evaluated, also showing that systemic diseases can negatively influence tissue responses to filling materials after endodontic treatment. Despite advances in endodontic medicine studies, there are still gaps in knowledge on the mechanisms of interactions between apical periodontitis (AP) and systemic diseases and much research to be done. In this sense, this critical narrative literature review aimed to show the evolution of studies in endodontic medicine to help the endodontist to know the role of systemic diseases in the pathogenesis of AP and the possible interference in the repair of periapical tissues after endodontic treatment, as well as to evidence the systemic complications that can be triggered or aggravated in the presence of endodontic infection.

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Section: Impact Of Systemic Disorders On Biomineralization Of Endodon...supporting

confidence: 82%

Evolution of endodontic medicine: a critical narrative review of the interrelationship between endodontics and systemic pathological conditions

et al. 2021

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“…Sixteen 2-month-old male Wistar rats weighing from 250 to 280 g were used. The sample size was established based on previous studies involving the analysis of materials in the subcutaneous tissue of rats (Cintra et al 2013, de Azevedo Queiroz et al 2018, Benetti et al 2018a. The animals were housed in a temperature-controlled environment (22 AE 1°C, 70% humidity) with a 12-h light-dark cycle and received water and food ad libitum.…”

Section: Biocompatibility and Biomineralization Analysismentioning

confidence: 99%

Biocompatibility, induction of mineralization and antimicrobial activity of experimental intracanal pastes based on glass and glass‐ceramic materials

et al. 2020

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“…Finally, it has been reported that systemic disease can influence the efficiency of MTA in endodontics. For instance, diabetes mellitus could inhibit mineral differentiation in subcutaneous implantation (de Azevedo et al, 2018) and dentin bridge formation in rat pulp capping (Garber et al, 2009). So when calcium silicate-based bioceramics are applied in patients with systemic disease, the control and treatment of the systemic disease should be carried out ahead of any procedures to improve the success rate of calcium silicatebased bioceramics in endodontics.…”

Section: Conclusion and Perspectivementioning

confidence: 99%

In vivo Biocompatibility and Bioactivity of Calcium Silicate-Based Bioceramics in Endodontics

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Sun

Chen

et al. 2020

Front. Bioeng. Biotechnol.

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Endodontic therapy aims to preserve or repair the activity and function of pulp and periapical tissues. Due to their excellent biological features, a substantial number of calcium silicate-based bioceramics have been introduced into endodontics and simultaneously increased the success rate of endodontic treatment. The present manuscript describes the in vivo biocompatibility and bioactivity of four types of calcium silicate-based bioceramics in endodontics.

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Systemic bone marker expression induced by grey and white mineral trioxide aggregate in normal and diabetic conditions

Cited by 9 publications

References 61 publications

Evolution of endodontic medicine: a critical narrative review of the interrelationship between endodontics and systemic pathological conditions

Evolution of endodontic medicine: a critical narrative review of the interrelationship between endodontics and systemic pathological conditions

Biocompatibility, induction of mineralization and antimicrobial activity of experimental intracanal pastes based on glass and glass‐ceramic materials

In vivo Biocompatibility and Bioactivity of Calcium Silicate-Based Bioceramics in Endodontics

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