Systemic cytomegalovirus masquerading as a colorectal mass in a patient with undiagnosed HIV/AIDS

Madala, N.; Silva, Rafael C. Da; Cardona, Jaime Gonzalez; Burdette, Elliot Boyd; Nlandu, Zola

doi:10.1016/j.idcr.2022.e01598

IDCases

2022

DOI: 10.1016/j.idcr.2022.e01598

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Systemic cytomegalovirus masquerading as a colorectal mass in a patient with undiagnosed HIV/AIDS

N. Madala

Rafael C. Da Silva

Jaime Gonzalez Cardona

et al.

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2024

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Cited by 1 publication

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Intestinal histoplasmosis and coinfections mimicking inflammatory bowel disease and neoplasia

Borges Domingues Batista,

Oliveira Guilarde,

De Souza Couto Eckert

et al. 2024

Sci Med

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Objectives: to describe a case series of chronic diarrhea of infectious etiology previously identified as Inflammatory Bowel Diseases (IBD). Case reports: we present four cases from a Brazilian tertiary hospital in which patients with HIV were initially treated for IBD or suspected neoplasia based on clinical presentation and colonoscopy findings. Late-stage HIV/AIDS diagnosis subsequently revealed disseminated histoplasmosis with intestinal involvement and coinfections, including cytomegalovirus colitis (n = 3) and tuberculosis (n = 1). Conclusions: chronic diarrhea, particularly when accompanied by dysenteric symptoms, presents significant challenges in distinguishing between Inflammatory Bowel Disease (IBD), neoplasia, and infectious diseases. This case series highlights the importance of considering immunosuppression, especially HIV/AIDS and related opportunistic infections, in cases of chronic diarrhea. A comprehensive diagnostic approach incorporating microbiological, serological, molecular, and histopathological analyses is critical in identifying underlying etiologies, including coinfections. Early and accurate diagnosis facilitates appropriate treatment, reducing the morbidity and mortality associated with these conditions.

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Intestinal histoplasmosis and coinfections mimicking inflammatory bowel disease and neoplasia

Borges Domingues Batista,

Oliveira Guilarde,

De Souza Couto Eckert

et al. 2024

Sci Med

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Systemic cytomegalovirus masquerading as a colorectal mass in a patient with undiagnosed HIV/AIDS

Cited by 1 publication

References 13 publications

Intestinal histoplasmosis and coinfections mimicking inflammatory bowel disease and neoplasia

Intestinal histoplasmosis and coinfections mimicking inflammatory bowel disease and neoplasia

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