Systemic effects of chronic obstructive pulmonary disease in young-old adults’ life-space mobility

Abstract

PurposeThe objective was to assess whether dyspnea, peripheral muscle strength and the level of physical activity are correlated with life-space mobility of older adults with COPD.Patients and methodsSixty patients over 60 years of age (40 in the COPD group and 20 in the control group) were included. All patients were evaluated for lung function (spirometry), life-space mobility (University of Alabama at Birmingham Study of Aging Life-Space Assessment), dyspnea severity (Modified Dyspnea Index), peripheral muscle strength (handgrip dynamometer), level of physical activity and number of daily steps (accelerometry). Groups were compared using unpaired t-test. Pearson’s correlation was used to test the association between variables.ResultsLife-space mobility (60.41±16.93 vs 71.07±16.28 points), dyspnea (8 [7–9] vs 11 [10–11] points), peripheral muscle strength (75.16±14.89 vs 75.50±15.13 mmHg), number of daily steps (4,865.4±2,193.3 vs 6,146.8±2,376.4 steps), and time spent in moderate to vigorous activity (197.27±146.47 vs 280.05±168.95 minutes) were lower among COPD group compared to control group (p<0.05). The difference was associated with the lower mobility of COPD group in the neighborhood.ConclusionLife-space mobility is decreased in young-old adults with COPD, especially at the neighborhood level. This impairment is associated to higher dyspnea, peripheral muscle weakness and the reduced level of physical activity.

Life‐Space Assessment questionnaire: Novel measurement properties for Brazilian community‐dwelling older adults

“…We showed that the LSA is valid for use in Brazil, and from now on practitioners and researchers will be able to assess lifespace mobility of Brazilian older adults and, plus, to advance on validation studies on specific conditions and other geriatric syndromes, as carried out for older adults with Chronic Obstructive Pulmonary Disease. 29 Therefore, we conclude that the LSA presents adequate reliability, validity and interpretability for lifespace mobility assessment of Brazilian communitydwelling older adults. Also, the LSA was convergent with levels of physical activity.…”

“…As one of the implications of the present study, we note the LSA is among few instruments that assesses participation and, despite its increasing use, many of the measurement properties were unclear; this might lead to incorrect use and interpretation of data, especially in cross‐culturally adapted versions. We showed that the LSA is valid for use in Brazil, and from now on practitioners and researchers will be able to assess life‐space mobility of Brazilian older adults and, plus, to advance on validation studies on specific conditions and other geriatric syndromes, as carried out for older adults with Chronic Obstructive Pulmonary Disease …”

Identifying Protein–metabolite Networks Associated with COPD Phenotypes

“…Chronic obstructive pulmonary disease (COPD) is the fourth leading cause of death in the United States [1]. While COPD patients have a history of tobacco smoke exposure, only a minority of smokers develop COPD [2].…”

<p>Activities of Daily Living and Life-Space Mobility in Older Adults with Chronic Obstructive Pulmonary Disease</p>

“…Therefore, in order to develop interventions aimed at improving functional independence and participation in social activities of older people with COPD, it is important to investigate the association between the systemic effects of COPD and life-space mobility. The University of Alabama at Birmingham Study of Aging Life-Space Assessment questionnaire has already been used in older people with COPD, 11 and a relationship between the systemic effects of COPD (such as dyspnea and peripheral muscle strength) and life-space mobility was found. 11 However, there is a lack of information on the relationship between the performance during activities of daily living and life-space mobility in this population.…”

“…The University of Alabama at Birmingham Study of Aging Life-Space Assessment questionnaire has already been used in older people with COPD, 11 and a relationship between the systemic effects of COPD (such as dyspnea and peripheral muscle strength) and life-space mobility was found. 11 However, there is a lack of information on the relationship between the performance during activities of daily living and life-space mobility in this population. Hence, the aim of the current study was to investigate whether limitation during the performance of activities of daily living was associated with life-space mobility in older people with COPD, and to generate a regression model for life-space mobility score.…”