Systemic Inflammatory Response and Cardiopulmonary Bypass

Akar, Ahmet; Inan, Bahadir; Punjabi, Karan P.; Dernek, Sadettin

doi:10.1007/978-3-031-14557-5_3

Cited by 1 publication

(1 citation statement)

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“…interleukin (IL-6 and IL-8) and other inflammatory mediators after on-pump cardiac surgery. SIRS has been observed in patients undergoing CPB, prompting the development of measures to avoid or reduce its recurrence [ 17 ]. Various interventions have been attempted to prevent or reduce SIRS, but their impact on outcomes is unclear [ 16 ].…”

Section: Discussionmentioning

confidence: 99%

Intensive care unit length of stay and mortality comparison between on-pump and off-pump coronary artery bypass graft: a retrospective study

Ibrahim

Joyo

2023

Egypt Heart J

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Background Recently, coronary artery bypass graft (CABG) techniques, both on-pump (ONCABG) and off-pump (OPCABG), were compared to seek the most effective approach to reduce the cost of prolonged intensive care unit length of stay (ICU LOS) and mortality. This study aims to compare ICU LOS and mortality in ONCABG and OPCABG. Results Demographic data of 1569 patients show the variance of characteristics. The analysis shows significant and longer ICU LOS in OPCABG than ONCABG (2.151 ± 0.100 vs. 1.573 ± 0.246 days; p = 0.028). Similar results were demonstrated after adjustment of covariates effects (3.146 ± 0.281 vs. 2.548 ± 0.245 days; p = 0,022). Logistic regression shows no significant difference in mortality in OPCABG and ONCABG, both in the unadjusted (OR [CI 95%] 1.133 [0.485–2.800]; p = 0.733) and the adjusted models (OR [CI 95%] 1.133 [0.482–2.817]; p = 0,735). Conclusion ICU LOS was significantly longer in OPCABG patients than in ONCABG patients in the author's centre. There was no significant difference in mortality between the two groups. This finding highlights a discrepancy between recently published theories and the practices observed in the author's centre.

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Section: Discussionmentioning

confidence: 99%