Systemic Lidocaine to Improve Postoperative Quality of Recovery After Ambulatory Laparoscopic Surgery

Oliveira, Gildàsio S. De; Fitzgerald, Paul C.; Streicher, Lauren; Marcus, R-Jay; McCarthy, Robert J.

doi:10.1097/01.sa.0000425551.15112.b7

Cited by 27 publications

(47 citation statements)

References 1 publication

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“…[9][10][11]15,16 Our results are consistent with those of previous studies in which intravenous lidocaine was found to improve postoperative analgesia. [9][10][11]16 Intraoperative lidocaine infusion reduced the postoperative pain and amount of analgesia requested in the postoperative anesthesia care unit in patients who underwent laparoscopic abdominal gynecologic surgery. 16 Systemic lidocaine improves postoperative quality of recovery in patients undergoing outpatient laparoscopy.…”

supporting

confidence: 83%

“…Patients who received lidocaine had less opioid consumption, which translated to a better quality of recovery. 9 Similarly, our group reported that intravenous lidocaine reduced postoperative pain intensity, fentanyl consumption and the administration frequency of PCA measured by the number of button pushes in the first 12 hours after inguinal herniorrhaphy. 10 Contrary to our findings, some studies have failed to demonstrate a significant analgesic effect of intravenous lidocaine during the postoperative period.…”

mentioning

confidence: 99%

“…[9][10][11] Furthermore, intravenous lidocaine is easy to administer. The benefits of lidocaine are enhanced by the drug's low expense, accessibility and safety.…”

mentioning

confidence: 99%

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Intraoperative systemic lidocaine for pre-emptive analgesics in subtotal gastrectomy: a prospective, randomized, double-blind, placebo-controlled study

et al. 2014

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Intraoperative systemic lidocaine for pre-emptive analgesics in subtotal gastrectomy: a prospective, randomized, double-blind, placebo-controlled study Background: Pre-emptive intravenous lidocaine infusion is known to improve postoperative pain in abdominal surgery. We assessed the effect of intravenous lidocaine infusion in patients who underwent subtotal gastrectomy. Methods:We conducted a double-blind, placebo-controlled study with patients undergoing subtotal gastrectomy for early gastric cancer divided into 2 groups: 1 group received intravenous lidocaine infusion preoperatively and throughout surgery, and the other received normal saline infusion (placebo). We assessed postoperative outcomes, including pain scores on a visual analogue scale (VAS), administration frequency of patient-controlled analgesia (PCA) and the amount of consumed fentanyl. Postoperative nausea and vomiting, length of hospital stay (LOS), time to return to regular diet and patient satisfaction at discharge were evaluated.Results: There were 36 patients in our study. Demographic characteristics were similar between the groups. The VAS pain scores and administration frequency of PCA were significantly lower in the lidocaine group until 24 hours after surgery, and fentanyl consumption was significantly lower in this group until 12 hours postoperatively compared with the placebo group. The total amount of consumed fentanyl and the total administration frequency of PCA were significantly lower in the lidocaine than the control group. No significant differences were detected in terms of nausea and vomiting, return to regular diet, LOS and patient satisfaction, and there were no reported side-effects of lidocaine. Conclusion:Intravenous lidocaine infusion reduces pain during the postoperative period after subtotal gastrectomy.

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confidence: 83%

mentioning

confidence: 99%

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Intraoperative systemic lidocaine for pre-emptive analgesics in subtotal gastrectomy: a prospective, randomized, double-blind, placebo-controlled study

et al. 2014

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“…Cardiac output affects the metabolism of DEX as mentioned earlier but it was not investigated. Third, the inclusion/exclusion criteria did not include administration of lidocaine 21,22) , which is considered to have a potential analgesic effect. Fourth, the initial and maximum doses of DEX were decided at the discretion of attending anesthesiologists or intensivists who were not blinded to weight of patients, which might have reflected to drug dose.…”

Section: Discussionmentioning

confidence: 99%

The Effect of Obesity on Dose of Dexmedetomidine When Administered With Fentanyl During Postoperative Mechanical Ventilation - Retrospective

Obara

Morimoto

Iseki

et al. 2015

FJMS

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: We carried out a retrospective investigation on the effect of obesity on dexmedetomidine (DEX) requirements when administered with fentanyl (FEN) during mechanical ventilation after major surgeries. After Institutional Review Board approval, 14 obese patients with a body mass index (BMI) ≥ 30 kg/m 2 and the same number of non -obese patients with similar backgrounds to the obese patients were selected from medical records. Doses of DEX in the first 48 h or until the end of sedation or extubation were calculated for comparison. In addition to comparison of dosing between the groups, associations between total body weight (TBW), BMI, and lean body mass (LBM) values and doses of DEX (mcg/h), between BMI and various indices (i.e., amount per TBW per hour and amount per LBM per hour) of DEX doses, and between above indices of DEX and FEN doses were also examined. There were no significant differences in DEX dose indices between the groups. However, DEX requirements (mcg/h) were significantly increased with TBW (kg) (r = 0.51, P = 0.003), BMI (r = 0.49, P = 0.006) and LBM (kg) (r = 0.42, P = 0.02), which might have enhanced the DEX metabolism with physiological changes with obesity. These findings will be beneficial for future clinical pharmacological analysis of DEX.

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“…The lidocaine infusion was terminated either at skin closure or the end of the surgical procedure [45,186,188,[190][191][192][193][194][195][196][197][198][199][200][201][202][203][204][205][206]; 1 h after surgery/skin closure [207][208][209][210][211][212]; 1 h after arrival in the post anaesthesia care unit (PACU) [213]; 4 h post-operatively [214]; up to 8 h post-operatively (or at PACU discharge whichever occurred earlier) [187]; after a total of 12 h [215]; 24 h post-operatively [216][217][218][219][220][221][222][223]; 48 h post-operatively [215,[224][225][226]; or on the day of return of bowel function or, at the latest, on the fifth post-operative day [189]. One study did not report the cessation time for the lidocaine infusion [227].…”

Section: Role Of Ivlt In Acute Perioperative Painmentioning

confidence: 99%

A Review of Intravenous Lidocaine Infusion Therapy for Paediatric Acute and Chronic Pain Management

Lauder¹

2017

Pain Relief - From Analgesics to Alternative Therapies

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Pediatric acute and chronic pain experiences involve the interaction of physiological, psychological, behavioural, developmental, pharmacological and situational factors. In the acute perioperative pain setting preventative multimodal analgesia is required to provide comfort and minimise the potential for "wind-up" and central sensitisation. When pain is recurrent, ongoing or chronic some children embark on a downward spiral of decreased physical, psychological and social functioning. The multidisciplinary team management approach is a well-established standard of care for children with complex chronic pain. Intravenous lidocaine has peripheral and central mediated analgesic, anti-inflammatory and anti-hyperalgesic properties. Intravenous lidocaine infusion therapy (IVLT) has been shown to be effective in the management of acute and chronic pain in adults. This chapter will present the rational for IVLT in pediatric pain management with emphasis on preventative multimodal therapy in acute pain and the multidisciplinary treatment approach in chronic pain. Large multi-centre randomised controlled trials are required to provide the evidence-base to confirm that IVLT is indeed an effective and safe treatment option in acute preventative multimodal analgesia and as an adjunct in the multidisciplinary care of chronic pain in the pediatric population. Keywords

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Systemic Lidocaine to Improve Postoperative Quality of Recovery After Ambulatory Laparoscopic Surgery

Cited by 27 publications

References 1 publication

Intraoperative systemic lidocaine for pre-emptive analgesics in subtotal gastrectomy: a prospective, randomized, double-blind, placebo-controlled study

Intraoperative systemic lidocaine for pre-emptive analgesics in subtotal gastrectomy: a prospective, randomized, double-blind, placebo-controlled study

The Effect of Obesity on Dose of Dexmedetomidine When Administered With Fentanyl During Postoperative Mechanical Ventilation - Retrospective

A Review of Intravenous Lidocaine Infusion Therapy for Paediatric Acute and Chronic Pain Management

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