2022
DOI: 10.7759/cureus.28746
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Systemic Lupus Erythematosus in the Elderly That Debuts With an Organic Manifestation of Lupus Nephritis

Abstract: Systemic lupus erythematosus (SLE) is a systemic autoimmune condition with many clinical presentations. It is classically seen in young to middle-aged females and can present with cutaneous, renal, serosal, hematological, joint, and/or neurological manifestations at the time of diagnosis or may develop over the course of the disease. Late-onset SLE or SLE in the elderly is a subtype that differs from the classic SLE in age group, clinical presentation, involvement of organs, and severity. Here, we present the … Show more

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Cited by 3 publications
(2 citation statements)
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“…Although recent advances in diagnosis and treatment have led to a remarkable improvement in the prognosis of SLE, 5 to 20% of patients continue to progress to end-stage renal disease within 10 years following the diagnosis of nephritis. [4,5] Childhood-onset SLE is rare, with an estimated annual incidence of 0.3 to 0.9/100,000 children. [6,7] The heterogeneous and complex nature of SLE means that diagnosis is often delayed until progression is advanced and several organs have become affected.…”
Section: Introductionmentioning
confidence: 99%
See 1 more Smart Citation
“…Although recent advances in diagnosis and treatment have led to a remarkable improvement in the prognosis of SLE, 5 to 20% of patients continue to progress to end-stage renal disease within 10 years following the diagnosis of nephritis. [4,5] Childhood-onset SLE is rare, with an estimated annual incidence of 0.3 to 0.9/100,000 children. [6,7] The heterogeneous and complex nature of SLE means that diagnosis is often delayed until progression is advanced and several organs have become affected.…”
Section: Introductionmentioning
confidence: 99%
“…Although recent advances in diagnosis and treatment have led to a remarkable improvement in the prognosis of SLE, 5 to 20% of patients continue to progress to end-stage renal disease within 10 years following the diagnosis of nephritis. [4,5]…”
Section: Introductionmentioning
confidence: 99%