2021
DOI: 10.7759/cureus.15517
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Systemic Lupus Erythematosus With Multi-Organ Involvement in a Young Female: Lymphadenopathy, Lupus Cerebritis, Lupus Nephritis, and Cardiac Manifestations

Abstract: Systemic lupus erythematosus (SLE) is a multisystemic autoimmune disease that can affect almost every organ in the body. Its complications can often be fatal. The fatal complications include lupus cerebritis, lupus nephritis, and cardiac manifestations such as pericardial effusion. In this report, we discuss the case of a 23-year-old female who presented with complaints of high-grade fever, seizures, and altered mental state (AMS) and was found to have generalized lymphadenopathy (LAP). Various blood and urine… Show more

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Cited by 2 publications
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“…Lupus cerebritis is a poorly defined disease entity, described by some researchers as a former term for NPSLE [3]. However, others have referred the evidence of cerebral parenchymal damage with cerebrospinal fluid (CSF) inflammation in the absence of stroke and vasculitis as lupus cerebritis [5]. Herein, we report a severe case of lupus cerebritis that was treated successfully with rituximab.…”
mentioning
confidence: 91%
“…Lupus cerebritis is a poorly defined disease entity, described by some researchers as a former term for NPSLE [3]. However, others have referred the evidence of cerebral parenchymal damage with cerebrospinal fluid (CSF) inflammation in the absence of stroke and vasculitis as lupus cerebritis [5]. Herein, we report a severe case of lupus cerebritis that was treated successfully with rituximab.…”
mentioning
confidence: 91%