1991
DOI: 10.1111/j.1365-2141.1991.tb08598.x
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Systemic Mastocytosis and Primary Thrombocythaemia

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1991
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Cited by 7 publications
(3 citation statements)
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“…Hydroxyurea is the first-choice drug for ET patients at high risk of thrombosis [14], i.e., those with a previous thrombotic event and/or over 60 years of age, and it may also be used in patients with SM-AHNMD. This drug, indeed, was shown to be effective in five out of the seven subjects with SM-ET described in Table 1 [8,9], including our patient.…”
Section: Discussionmentioning
confidence: 78%
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“…Hydroxyurea is the first-choice drug for ET patients at high risk of thrombosis [14], i.e., those with a previous thrombotic event and/or over 60 years of age, and it may also be used in patients with SM-AHNMD. This drug, indeed, was shown to be effective in five out of the seven subjects with SM-ET described in Table 1 [8,9], including our patient.…”
Section: Discussionmentioning
confidence: 78%
“…Myelodysplastic syndromes, acute myeloid leukemia and chronic myelomonocytic leukemia have been reported to be the hematological diseases most commonly associated with SM [7], whilst classical or unclassifiable myeloproliferative neoplasms have been seldom described as co-morbidities. At our knowledge, only 15 cases of SM associated with essential thrombocythemia have been published so far, seven of which are described in detail in Table 1 [8,9,10] (lesions of the osseous spine were found in four patients, urticaria pigmentosa in two and splenomegaly only in one). As in our case report, SM was diagnosed in one patient during screening for thrombocytosis [8].…”
Section: Discussionmentioning
confidence: 99%
“…Other cases show proliferation of lineages other than mast cell (erythroid, granulocytic or megakaryocytic) and meet the criteria for various myeloproliferative disorders. Diagnoses made have included chronic myeloid leukaemia (Horny et al , 1990), polycythaemia rubra vera (Travis et al , 1998b), essential thrombocythaemia (Travis et al , 1988b; Krsnik et al , 1991; Le Tourneau et al , 1991) and agnogenic myeloid metaplasia (Horny et al , 1990; Nagata et al , 1995). In some patients with striking eosinophilia and consequent tissue damage a diagnosis of ‘idiopathic hypereosinophilic syndrome’ has been made (Parker, 1991b); it is possible, although not certain, that such cases represent a chronic eosinophilic leukaemia.…”
Section: Table I Classification Of Mast Cell Neoplasms (Metcalfe 19mentioning
confidence: 99%