Systemic oxygen uptake during hypothermic cardiopulmonary bypass

Alston, R. Peter; Singh, Mohan; McLaren, Alistair

doi:10.1016/s0022-5223(19)34298-9

Cited by 44 publications

(11 citation statements)

References 31 publications

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“…Several risk status models have been developed to predict outcome after cardiac operations. [7][8][9] Monitoring of such factors during the early postoperative hours may enhance early therapeutic interventions that might improve the outcome. Although many clinical and biochemical parameters are still in use for the determination of patients with high risk of morbidity and mortality, the authors believe that a simpler and accurate predictor of risk should be established in the pediatric age group.…”

Section: Discussionmentioning

confidence: 99%

Serum Lactate Level Has Prognostic Significance After Pediatric Cardiac Surgery

Başaran

Sever

Kafali

et al. 2006

Journal of Cardiothoracic and Vascular Anesthesia

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Section: Discussionmentioning

confidence: 99%

Serum Lactate Level Has Prognostic Significance After Pediatric Cardiac Surgery

Başaran

Sever

Kafali

et al. 2006

Journal of Cardiothoracic and Vascular Anesthesia

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“…After computing total points for an individual patient, the risk of CNS injury can be determined by plotting the total points received against the risk score at the bottom of the nomogram. For example, 100 points predict a 5% risk of CNS injury. Reprinted with permission from Newman MF, Wolman R, Kanchuger M, et al: Multicenter preoperative stroke risk index for patients undergoing coronary artery bypass graft surgery.…”

Section: Atheromatous Diseasementioning

confidence: 99%

Strategies to Protect the Brain During Cardiac Surgery

Newman

Stanley

Grocott

2000

Semin Cardiothorac Vasc Anesth

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Despite significant advances in cardiopulmonary by pass (CPB) technology, surgical techniques, and anes thetic management, central nervous system (CNS) com plications remain a common and costly problem after CPB. Stroke is often considered a rare and unprevent able complication of cardiac surgery. Recent studies have shown that through the use of echocardiography and historical risk stratification strategies, we can de fine which patients are at substantially greater risk for CNS injury. Through enhanced understanding of the etiology of stroke and perioperative factors, which are associated with potential for neuroprotection or injury extension, there now exists a greater potential than ever to substantially reduce neurological injury associ ated with cardiac surgery. Strategies and theories of stratifying patients at risk and secondarily reducing that risk are described, as well as consideration for early postoperative assessment to allow treatment when events occur.

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“…9 On the other hand, several clinical studies have been unable to detect a benefit associated with PP. [10][11][12][13][14][15] Although the subject has been discussed frequently during the past decades, studies have advocated conflicting recommendations. As a result, the optimal perfusion characteristic during CPB is still in debate.…”

mentioning

confidence: 99%