2015
DOI: 10.3402/ecrj.v2.26761
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Systemic sarcoidosis mimicking malignant metastatic disease

Abstract: We present a case of systemic sarcoidosis involving the liver, pancreas, lungs, mediastinal and intraabdominal lymph nodes and bones. Multiple organ system manifestations mimicked malignant metastatic disease. The diagnosis was established with clinical, radiological, and pathological findings after neoplasm was ruled out by pathological tests. The patient showed rapid symptom remission with systemic steroid treatment.

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Cited by 38 publications
(8 citation statements)
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References 13 publications
(28 reference statements)
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“…On excisional biopsy, however, the cervical lymph nodes showed a picture typical of sarcoidosis 52. A few more case reports mirror our cases in that the patient presents with multisystemic sarcoidosis involving the liver and bones as well 53 54. In their case report,53 Hammen et al presented a case with systemic sarcoidosis involving the liver, pancreas, lungs, mediastinal and intra-abdominal lymph nodes, and bones.…”
Section: Systemic Inflammatory Diseasessupporting
confidence: 73%
See 1 more Smart Citation
“…On excisional biopsy, however, the cervical lymph nodes showed a picture typical of sarcoidosis 52. A few more case reports mirror our cases in that the patient presents with multisystemic sarcoidosis involving the liver and bones as well 53 54. In their case report,53 Hammen et al presented a case with systemic sarcoidosis involving the liver, pancreas, lungs, mediastinal and intra-abdominal lymph nodes, and bones.…”
Section: Systemic Inflammatory Diseasessupporting
confidence: 73%
“…A few more case reports mirror our cases in that the patient presents with multisystemic sarcoidosis involving the liver and bones as well 53 54. In their case report,53 Hammen et al presented a case with systemic sarcoidosis involving the liver, pancreas, lungs, mediastinal and intra-abdominal lymph nodes, and bones. The diagnosis of sarcoidosis was confirmed by the presence of non-caseating granulomas on ultrasound-guided liver biopsy and transbronchial biopsy, and the patient received systemic glucocorticoids as appropriate treatment for the condition.…”
Section: Systemic Inflammatory Diseasessupporting
confidence: 65%
“…Estimation on the incidence rate and prevalence proportion of sarcoidosis in Puerto Rico might have been affected by possible inaccuracies in the use of ICD codes assigned by the health care providers to diagnose sarcoidosis. Since sarcoidosis may mimic other chronic inflammatory or even malignant metastatic disease, 36 the risk of misclassification or over diagnosis of sarcoidosis cannot be excluded. The identification of sarcoidosis was based on diagnostic claims; therefore, we were unable to confirm the sarcoidosis cases through the access of medical records data (i.e.…”
Section: Discussionmentioning
confidence: 99%
“…Clearly de ned nodules in organ's tissue can mimic disseminated malignancy. 10,11 Apart from nodular form of sarcoidosis, there are other granulomatous diseases that may lead to multiple nodules in the lungs, giving the impression of lung metastases, such as histoplasmosis and pulmonary hyalinizing granuloma 12,13 . Adding to the confusion, a number of other diseases can produce multiple pulmonary nodules, including pneumoconiosis, infectious (such as disseminated tuberculosis, invasive aspergillosis, chickenpox and measles), noninfectious in ammatory diseases (rheumatoid nodules, Wegener's granulomatosis), arteriovenous malformations, amyloid and infarcts 11 .…”
mentioning
confidence: 99%