Systemic Versus Topical Corticosteroids in the Treatment of DRESS: A Retrospective Cohort Study Followed by a Meta-Analysis

Lian, Bertrand ShengYang; Ha, Judy H.; Sultana, Rehena; Chan, Linus; Choo, Karen Jui Lin; Yeo, Yoomi; Lee, Haur Yueh

doi:10.1007/s40257-023-00776-6

Cited by 1 publication

(1 citation statement)

References 30 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Patients treated with IV corticosteroids had a higher risk of infectious complications; however, no difference in mortality or hospital stay was found. The study concludes that the use of topical corticosteroids is controversial, but may be a safe and effective alter-native, but with a slow response in mild-moderate DRESS [25]. Treatment with IV steroids should not be changed rapidly to topical therapy; instead should be tapered progressively in order to prevent relapses, even when the clinical evolution is favorable [26].…”

Section: Allopurinol Kidney Carbamazepinementioning

confidence: 99%

DRESS and Stevens–Johnson Syndrome Overlap Secondary to Allopurinol in a 50-Year-Old Man—A Diagnostic and Treatment Challenge: Case Report

Martínez,

Franco,

Sáenz

et al. 2023

Life

View full text Add to dashboard Cite

Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a drug reaction commonly related to eosinophilia, from uncertain epidemiology, and without consensus for diagnosis and treatment globally. It presents a great challenge in its management and is characterized by fever, lymphadenopathy, skin rash, and multisystemic involvement. An aggressive and difficult-to-manage clinical case is presented in a 50-year-old man with chronic kidney disease due to diabetes mellitus type 2 and systemic arterial hypertension, who developed an unusual variant similar to DRESS and Stevens–Johnson syndrome (SJS) overlap secondary to allopurinol, with skin manifestations without eosinophilia, but fulfilling clinical and laboratory criteria for DRESS and SJS syndrome.

show abstract

Section: Allopurinol Kidney Carbamazepinementioning

confidence: 99%