Systems Approach to Process Lifecycle Engineering in Pharmaceutical Production

2017

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The process and plant design stages, in particular the preliminary process design (PPD) stage, are performed repeatedly to cope with environmental changes at a plant during its lifecycle. The stages after the original design are called revamp design stages. As the PPD is repeated, operational exibility is decreased. As a result, slight deviations from the intended critical process conditions during operation can lead to problems. However, in many cases, the causes of an operational problem are not identi ed, leading to safety issues. To overcome this, a framework including two Business Process Models (BPMs) is developed and modeled using IDEF0 with a hierarchical nature and ability to describe the PDCA engineering cycle. One BPM is developed to acquire the information on critical process conditions generated in the PPD stage. The other BPM is developed to systematize the acquired generated information into technology for the PPD by associating the information with design variables. The former BPM must rst be developed as a reference model for the latter as a requirement. Furthermore, the framework is clearly divided into the above-mentioned two BPMs to manage the technology throughout the plant lifecycle while keeping consistent linkage to each other. Finally, it is con rmed that the developed framework has the necessary structure to systematize the technology of the PPD throughout the plant lifecycle by tracing a practical example problem of a distillation column in the framework.

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Section: Previous Studiesmentioning

confidence: 99%

A Framework to Systematize Technology of Preliminary Process Design for Plant Lifecycle Engineering

Yamada

Kawamura

2017

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Process Safety Management Based on the Business Process Model of Engineering Activities

Shimada

Kitajima

et al. 2015

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There has been a recent surge in the number of disasters and incidents occurring in the process industry (e.g., the petrochemical, chemical, food and pharmaceutical industries). The reasons thereof include defects in process safety management (PSM); inadequate safety management systems in companies; inadequate knowledge among managers and insu cient information about the tasks undertaken and resultant erroneous operation and/or misjudgment; no standardization for the PSM activity; and other engineering factors. The purpose of PSM is to prevent industrial accidents by the establishment of the PSM system at the company level as well as an improvement in safety engineering techniques. Safety of chemical process plants can be achieved throughout the plant-lifecycle engineering (Plant-LCE), which is performed from research and development until to plant safety design, construction, and manufacturing (production and maintenance) stages. For systematic PSM, a model-based engineering framework is needed so that information can be used to inform all stages of the plant-lifecycle. Constantly updated and revised data and information must be shared at each engineering stage in a transparent way in order to examine the impacts of the safety decisions in all activities of the chemical process plant. The present paper reviews the existing studies on business process models, which have been developed for the process industrial activities, and introduces an integrated PSM framework which makes it possible to realize a consistent and collaborative PSM.

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Analysis of Design Process for Engineering Plastic Parts with Developed Consistent Business Process Model

Shibata

2017