Systems biology and livestock production

Headon, Denis J.

doi:10.1017/s1751731113000980

Cited by 6 publications

(4 citation statements)

References 19 publications

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“…Systems biology is a key subfield of vetinformatics and has made great contributions to the modeling and simulation of biological systems (101)(102)(103). The field aids in the integration of multi-omics data, including genomics, proteomics, metabolomics, and transcriptomics, in order to construct models that comprehensively characterize the behavior of biological systems under various conditions (104).…”

Section: Systems Biology and Integration Of Multi-omics Datamentioning

confidence: 99%

“…In the past, researchers were forced to focus on single genes or proteins, but as omics technology and systems biology have advanced, the paradigm has changed from a reductionist approach to a holistic approach (104). Through network modeling and analysis, systems biology enables prediction of the behavior of whole systems and identification of essential components involved in various biological processes, both of which ultimately contribute to advancements in animal welfare and livestock productivity (101)(102)(103)(104).…”

Section: Systems Biology and Integration Of Multi-omics Datamentioning

confidence: 99%

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Vetinformatics from functional genomics to drug discovery: Insights into decoding complex molecular mechanisms of livestock systems in veterinary science

Pathak

Kim

2022

Front. Vet. Sci.

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Having played important roles in human growth and development, livestock animals are regarded as integral parts of society. However, industrialization has depleted natural resources and exacerbated climate change worldwide, spurring the emergence of various diseases that reduce livestock productivity. Meanwhile, a growing human population demands sufficient food to meet their needs, necessitating innovations in veterinary sciences that increase productivity both quantitatively and qualitatively. We have been able to address various challenges facing veterinary and farm systems with new scientific and technological advances, which might open new opportunities for research. Recent breakthroughs in multi-omics platforms have produced a wealth of genetic and genomic data for livestock that must be converted into knowledge for breeding, disease prevention and management, productivity, and sustainability. Vetinformatics is regarded as a new bioinformatics research concept or approach that is revolutionizing the field of veterinary science. It employs an interdisciplinary approach to understand the complex molecular mechanisms of animal systems in order to expedite veterinary research, ensuring food and nutritional security. This review article highlights the background, recent advances, challenges, opportunities, and application of vetinformatics for quality veterinary services.

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Section: Systems Biology and Integration Of Multi-omics Datamentioning

confidence: 99%

Section: Systems Biology and Integration Of Multi-omics Datamentioning

confidence: 99%

Vetinformatics from functional genomics to drug discovery: Insights into decoding complex molecular mechanisms of livestock systems in veterinary science

Pathak

Kim

2022

Front. Vet. Sci.

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“…Building an integrated phenotyping (Headon, 2013) that sorts out mechanisms underlying adaptability in an order of importance now needs to combine biological, bioinformatics and statistic knowledge.…”

Section: The Key Role Of Animal Adaptability To Connect Evolutionary and Animal Production Sciencesmentioning

confidence: 99%

When scientific communities intertwine

Ezanno¹

2020

PCI Anim Sci

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1. Wild and farmed animals are key elements of natural and managed ecosystems that deliver functions such as pollination, pest control and nutrient cycling within the broader roles they play in contributing to biodiversity and to every category of ecosystem services. They are submitted to global changes with a profound impact on the natural range and viability of animal species, the emergence and spatial distribution of pathogens, land use, ecosystem services and farming sustainability. We urgently need to improve our understanding of how animal populations can respond adaptively and therefore sustainably to these new selective pressures.2. In this context, we explored the common points between animal production science and animal ecology to identify promising avenues of synergy between communities through the transfer of concepts and/or methodologies, focusing on seven concepts that link both disciplines. Animal adaptability, animal diversity (both within and between species), selection, animal management, animal monitoring, agroecology and viability risks were identified as key concepts that should serve the cross-fertilization of both fields to improve ecosystem resilience and farming sustainability. The need for breaking down interdisciplinary barriers is illustrated by two representativeexamples: i) the circulation and reassortment of pathogens between wild and domestic animals and ii) the role of animals in nutrient cycles; i.e. recycling nitrogen (N), phosphorus (P), and carbon (C) through, for example, contribution to soil fertility and carbon sequestration. 4. Our synthesis identifies the need for knowledge integration techniques supported by programs and policy tools that reverse the fragmentation of animal research towards a unification into a single Animal Research Kinship, OneARK, which sets new objectives for future science policy.5. At the interface of animal ecology and animal production science, our article promotes an effective application of the agroecology concept to animals and the use of functional diversity to increase resilience in both wild and farmed systems. It also promotes the use of novel monitoring technologies to quantify animal welfare and factors affecting fitness. These measures are needed

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“…Controlling livestock pollution will account a lot for the management of NPS pollution in areas with high livestock intensity (Headon 2013;Ouyang et al 2013). Many measures have been taken to reduce livestock pollution in both domestic and abroad.…”

Section: Responsible Editor: Philippe Garriguesmentioning

confidence: 99%

Spatio-temporal characteristics of livestock and their effects on pollution in China based on geographic information system

Liu

et al. 2016

Environ Sci Pollut Res

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Livestock pollution, caused by rural household's scatter breeding mainly, is one of the major non-point sources. Different animal manures are abundant with different nutrients. Adopting the policies, management practices, and technologies related to livestock production based on livestock structure analysis can improve the efficiency on preventing pollution. Based on statistical data, the component structure of livestock was analyzed and corresponding effect on pollution was evaluated during the period of 1992-2012 in China. The results showed that the average annual growth rate (AAGR) of total China was 1.58 % during the 20 years. Larger amounts of livestock were concentrated in Southwest China and East China. In the view of component structure, each type of livestock had different distribution characteristics and constant increasing amounts were presented during the 20 years. Cattle took the largest proportion in almost every province, and the number of heads was over 40 % of all the livestock quantity for most provinces. Pollution of total nitrogen (TN), total phosphorus (TP), and chemical oxygen demand (COD) caused by livestock excretion in East and Southeast China was much more serious than that in other regions. However, the load of COD was far less than that of TN and TP. Cattle accounted most for the livestock pollution, and swine was the second one. The intensity characteristics of TN, TP, and COD were different from that of total pollution loads. The spatio-temporal characteristics of amounts and component structure of livestock were influenced by three kinds of factors (natural, economic, and social), such as climate, topography, modes of production, feed grain sector, related policies, and area of the study regions. Different livestock excrements had different impacts on environment. According to various livestock structures and economy conditions, different disposal methods should be adopted.

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Systems biology and livestock production

Cited by 6 publications

References 19 publications

Vetinformatics from functional genomics to drug discovery: Insights into decoding complex molecular mechanisms of livestock systems in veterinary science

Vetinformatics from functional genomics to drug discovery: Insights into decoding complex molecular mechanisms of livestock systems in veterinary science

When scientific communities intertwine

Spatio-temporal characteristics of livestock and their effects on pollution in China based on geographic information system

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