Systems biomedicine: It’s your turn —Recent progress in systems biomedicine

Abstract

The concept of “systems biology” is raised by Hood in 1999. It means studying all components with a systematic view. Systems biomedicine is the application of systems biology in medicine. It studies all components in a whole system and aims to reveal the patho‐physiologic mechanisms of disease. In recent years, with the development of both theory and technology, systems biomedicine has become feasible and popular. In this review, we will talk about applications of some methods of omics in systems biomedicine, including genomics, metabolomics (proteomics, lipidomics, glycomics), and epigenomics. We will particularly talk about microbiomics and omics for common diseases, two fields which are developed rapidly recently. We also give some bioinformatics related methods and databases which are used in the field of systems biomedicine. At last, some examples that illustrate the whole biological system will be given, and development for systems biomedicine in China and the prospect for systems biomedicine will be talked about.

Problems, challenges and promises: perspectives on precision medicine

“…The practice of medicine is currently undergoing a paradigm shift from the primarily reactive medicine of the past to a more proactive predictive medicine aimed at disease prevention [1][2][3][4][5][6][7][8][9]. Rather than treating a disease, there is a shift towards the treatment of individual patients, based on a personalised data driven approach.…”

Capturing the opportunities to initiate an in-depth integration of traditional Chinese medicine and western medicine

“…Furthermore, systems biomedicine encompasses all components of a biological system under certain conditions in which several methods, such as bioinformatics, are employed to reveal the complex interactions of these components and factors. Systems biomedicine also advocates all-directional, three-dimensional, and multi-perspective studies on whole life and disease processes, in which subjects (doctors/researchers) treat objects (patients/participants) individually [2].…”

Knowledge and awareness of precision medicine among dental students

“…Many researches have been conducted in favour of social insurance understudies in biobanking and biospecimen gifts. Many investigations were made to assess the information on precision medicine to analyse the given biospecimens and the variable inspecting their mentalitie (Zhang et al, 2013). The accuracy medication idea vows to accomplish a move to future social insurance frameworks with an increasingly proactive and persistent way to deal with medication.…”