Systolic aortic regurgitation: A not-so-rare phenomenon

Saura, Daniel; Oliva, María J.; Peñafiel, Pablo; Morena, Gonzalo de la; Valdés, Mariano

doi:10.1016/j.ijcard.2009.09.559

Cited by 3 publications

(7 citation statements)

References 8 publications

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“…As ventricular systole is sometimes unable to overcome aortic arterial pressure, aortic regurgitation during the whole systole may occur. The phenomenon of systolic aortic regurgitation has been described in patients with syncope [3] and heart failure [4], and rather than a physiological oxymoron, is not an exceptional finding in clinical practice [4,5]. We present the case of a patient with systolic aortic regurgitation immediately after TAVI.…”

mentioning

confidence: 95%

A simple echo-Doppler sign to assess improved myocardial performance after transcatheter aortic valve implantation

Saura¹,

Oliva-Sandoval

González-Carrillo

et al. 2012

International Journal of Cardiology

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mentioning

confidence: 95%

A simple echo-Doppler sign to assess improved myocardial performance after transcatheter aortic valve implantation

Saura¹,

Oliva-Sandoval

González-Carrillo

et al. 2012

International Journal of Cardiology

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“…Systolic aortic regurgitation has been regarded as a curious quirk with little clinical value, beyond its worth as an echocardiographic quiz or as physiological oxymoron. The frequency of SAR is low, but perhaps it is an overlooked phenomenon as its explanation seems counterintuitive . Presence of SAR in an echocardiographic study should be detected and reported as it may be clinically useful.…”

Section: Discussionmentioning

confidence: 98%

“…An exploratory study found that SAR was specifically associated with HF , but diagnostic accuracy could not be reported. Echocardiographic demonstration of SAR is infrequent but not exceptional . The main function of the heart is to transform biochemical energy into mechanical pressure to make blood flow in an organized and uninterrupted way.…”

Section: Introductionmentioning

confidence: 99%

Accuracy of systolic aortic regurgitation in the diagnosis of heart failure: a predictive approach

et al. 2014

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“…Like systolic AR, physicians are acquired to focus more on systolic PR. 1 , 2 , 3 , 4 , 5 , 6 , 7 Before elucidating systolic PR, systolic AR might provide some clues. Based on data, the prevalence of systolic AR is higher in HF population (5.9% vs. 2.1%).…”

Section: Discussionmentioning

confidence: 99%

“…Systolic AR had been identified in valvular heart disease or heart failure (HF) and showed capability for predicting HF. 1 , 2 , 3 , 4 , 5 , 6 Systolic AR was explained as the inability of the ventricular contraction to overcome the aortic pressure in patients with valvular incompetence. This phenomenon is associated with pulsus alternans and ineffective contraction, which is common in severe left‐side HF.…”

Section: Introductionmentioning

confidence: 99%

Systolic pulmonary regurgitation affects the outcome of patients with severe systolic heart failure

Hsiao

Chiou

2021

ESC Heart Failure

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Aims Little is known of the impact of systolic pulmonary regurgitation (PR) on acute decompensated heart failure (HF). We assessed the prevalence and prognostic significance of systolic PR in patients with severe HF. Methods and results According to recent 10 year echocardiographic database of E‐Da Hospital, 533 patients admitted for first systolic heart failure (HF) and left ventricular ejection fraction <35% were under investigation. Systolic PR was defined as the presence of pulmonary backward flow persistent after QRS in electrocardiogram. Isovolumic contraction/relaxation time and myocardial performance index were derived by tissue Doppler imaging. Right ventricular (RV) function was assessed by RV fractional area change. Estimated pulmonary vascular resistance (PVR) was assessed by the ratio of peak tricuspid regurgitation velocity to the RV outflow tract time–velocity integral. The factors associated with systolic PR were assessed by multivariate logistic regression. Cox proportional regression analyses were used to estimate the impact of cardiovascular events including HF rehospitalization and cardiovascular death. For estimated prevalence of 5480 control subjects, echocardiographic screens in those with normal left ventricular ejection fraction were performed. Of 533 systolic HF cases, 143 (26.8%) had systolic PR during indexed hospitalization. Among 143 cases, 86% systolic PR disappeared during late follow‐up. In control subjects, 0.3% (18/5480) had systolic PR. Systolic PR correlated to RV dysfunction, estimated PVR, E/e′, sign of low cardiac output, and pulmonary oedema. Systolic PR was associated independently with further cardiovascular events (hazard ratio 2.266, 95% confidence interval 1.682–3.089, P < 0.0001) including cardiovascular death and HF rehospitalization. Conclusions Systolic PR is not uncommon in systolic HF and is associated with high PVR and RV dysfunction. Systolic PR significantly impacts cardiovascular outcome.

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Systolic aortic regurgitation: A not-so-rare phenomenon

Cited by 3 publications

References 8 publications

A simple echo-Doppler sign to assess improved myocardial performance after transcatheter aortic valve implantation

A simple echo-Doppler sign to assess improved myocardial performance after transcatheter aortic valve implantation

Accuracy of systolic aortic regurgitation in the diagnosis of heart failure: a predictive approach

Systolic pulmonary regurgitation affects the outcome of patients with severe systolic heart failure

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