Systolic Time Ratio by Impedance Cardiography to Distinguish Preserved vs Impaired Left Ventricular Systolic Function in Heart Failure

Thompson, Brenda; Drazner, Mark H.; Dries, Daniel L.; Yancy, Clyde W.

doi:10.1111/j.1751-7133.2008.00001.x

Cited by 18 publications

(21 citation statements)

References 16 publications

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“…In healthy subjects, hyperoxaemia increases the pulmonary blood flow and decreases the HR, but CO is only slightly changed [22]. According to a study by Thompson et al, STR (PEP/LVET) measurement can be a reliable method for evaluation of ventricular systolic function, and differentiate patients with preserved and impaired ventricular systolic function [23]. In observations in the presented study, STR was elevated in the sitting position, which indicates impaired ventricular systolic function.…”

Section: Discussionsupporting

confidence: 44%

Non-invasive assessment of haemodynamic parameters in patients after Fontan procedure

Gutknecht

Kwiatkowska

Wałdoch

et al. 2020

Ann Agric Environ Med.

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Introduction and objective.Single ventricle anomaly is one of the complex congenital heart defects. A dependable non-invasive method of evaluation of Fontan circulation haemodynamics for early diagnosing unstable patients is hardly available in routine clinical practice. The aim of the study is non-invasive evaluation of the haemodynamic parameters in patients after Fontan operation. Materials and method. The study involved 11 participants (age 24.4±4.3 years) with functionally univentricular hearts after Fontan operation. Evaluation of haemodynamic parameters was performed in supine and sitting positions using the impedance cardiography method. Results. In comparative analysis, heart rate (70.1 vs.78.3 1/min; p=0.001), diastolic blood pressure (73.9 vs. 76.7 mm Hg; p=0.026), mean arterial blood pressure (84.5 vs. 88.0 mm Hg; p=0.013), systemic vascular resistance (1284.8 vs. 1334.9 dyn*s*cm -5 ; p=0.024), systemic vascular resistance index (2178.7 vs. 2272.8 dyn*s*cm -5 *m 2 ; p=0.018), pre-ejection period (124.2 vs. 136.2 ms; p=0.009), systolic time ratio (0.43 vs. 0.53; p=0.0001), and Zo (26.2 vs. 28.7 Ω; p<0.00001), were significantly higher in the sitting position. Stroke volume (75.4 vs. 68.5 ml; p=0.013), stroke index (42.7 vs. 39.0 ml*m -2 ; p=0.014), thoracic fluid content (38.5 vs. 35.4 1*kΩ -1 ; p=<0.00001), thoracic fluid content index (22.8 vs. 21.0 1*kΩ -1 *m -2 ; p=<0.00001), and leftventricular ejection time 291.1 vs. 260.1 ms; p=<0.00001, were significantly higher in the supine position. Conclusions. In patients after Fontan procedure, impedance cardiography can be a useful tool the assessment of shortterm haemodynamic changes provoked by postural changes. Its clinical value in patients with congenital heart defects should be further investigated.

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Section: Discussionsupporting

confidence: 44%

Non-invasive assessment of haemodynamic parameters in patients after Fontan procedure

Gutknecht

Kwiatkowska

Wałdoch

et al. 2020

Ann Agric Environ Med.

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“…Evaluation of left ventricular function was the subject in previous studies with ICG but none of the parameters we found associated with EF was previously regarded as a determinant of left ventricular systolic dysfunction. Systolic time ratio, however, was able to distinguish preserved from impaired EF [17]. Also, a close correlation between systolic time ratio and changes in EF was observed before and after treatment in patients with heart failure [18].…”

Section: Discussionmentioning

confidence: 99%

Comparing impedance cardiography and echocardiography in the assessment of reduced left ventricular systolic function

et al. 2013

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BackgroundAn early and accurate diagnosis of chronic heart failure is a big challenge for a general practitioner. Assessment of left ventricular function is essential for the diagnosis of heart failure and the prognosis. A gold standard for identifying left ventricular function is echocardiography. Echocardiography requires input from specialized care and has a limited access in Swedish primary health care. Impedance cardiography (ICG) is a noninvasive and low-cost method of examination. The survey technique is simple and ICG measurement can be performed by a general practitioner. ICG has been suggested for assessment of left ventricular function in patients with heart failure. We aimed to study the association between hemodynamic parameters measured by ICG and the value of ejection fraction as a determinant of reduced left ventricular systolic function in echocardiography.MethodsA non-interventional, observational study conducted in the outpatients heart failure unit. Thirty-six patients with the diagnosis of chronic heart failure were simultaneously examined by echocardiography and ICG. Distribution of categorical variables was presented as numbers. Distribution of continuous variables was presented as a mean and 95% Confidence Interval. Kruskal-Wallis test was used to compare variables and show differences between the groups. A p-value of <0.05 was considered significant.ResultsWe found that three ICG parameters: pre-ejection fraction, left ventricular ejection time and systolic time ratio were significantly associated with ejection fraction measured by echocardiography.ConclusionsThe association which we found between EF and ICG parameters was not reported in previous studies. We found no association between EF and ICG parameters which were suggested previously as the determinants of reduced left ventricular systolic function.The knowledge concerning explanation of hemodynamic parameters measured by ICG that is available nowadays is not sufficient to adopt the method in practice and use it to describe left ventricular systolic dysfunction.

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“…These early glycation products undergo further complex reaction, such as rearrangement, dehydration and condensation, to become irreversibly cross-linked, heterogeneous fluorescent derivatives, termed advanced glycation end products (AGEs) [1]. The formation and accumulation of AGEs have been known to progress under oxidative stress conditions such as diabetes and insulin resistance [1,2]. There is a growing body of evidence that AGEs are implicated in a variety of disorders such as vascular complications of diabetes, Alzheimer's disease and insulin resistance [1][2][3][4].…”

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confidence: 99%

“…Biompedance is a method of body composition analysis studied in HF in different ways such as impedance cardiography [2] or as a home monitoring method in telemedicine systems [3], but little data exist about the analysis of the components of the impedance vector (BIVA-Bioimpedance Vector Analysis-) in HF. The result of a measurement using bioelectrical impedance is a vector (Z vector) in which the opposition of an alternating current flow through intra-and extracellular ionic solutions is resistance (R), and the capacitance of biological tissues, is reactance (Xc).…”

mentioning

confidence: 99%

“…The formation and accumulation of AGEs have been known to progress under oxidative stress conditions such as diabetes and insulin resistance [1,2]. There is a growing body of evidence that AGEs are implicated in a variety of disorders such as vascular complications of diabetes, Alzheimer's disease and insulin resistance [1][2][3][4]. Indeed, we have recently found that AGEs attenuate cellular insulin sensitivity in cultured adipocytes and hepatoma cells and that serum level of AGEs is independently correlated with insulin resistance in non-diabetic subjects [2,4,5].…”

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confidence: 99%

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Bioelectrical impedance vector analysis (BIVA) in stable and non-stable heart failure patients: A pilot study

Gastelurrutia

Nescolarde

Rosell

et al. 2011

International Journal of Cardiology

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Systolic Time Ratio by Impedance Cardiography to Distinguish Preserved vs Impaired Left Ventricular Systolic Function in Heart Failure

Cited by 18 publications

References 16 publications

Non-invasive assessment of haemodynamic parameters in patients after Fontan procedure

Non-invasive assessment of haemodynamic parameters in patients after Fontan procedure

Comparing impedance cardiography and echocardiography in the assessment of reduced left ventricular systolic function

Bioelectrical impedance vector analysis (BIVA) in stable and non-stable heart failure patients: A pilot study

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