2021
DOI: 10.4049/jimmunol.206.supp.113.06
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T-bet+ B cells promote adipose tissue inflammation and metabolic disorder during obesity.

Abstract: Obesity is a public health crisis affecting a large and ever-growing portion of the global population. Obesity is associated with an increased risk of death and comorbidities, resulting in lower quality of life for obese patients and increased economic costs on healthcare systems. Obesity is linked with a low-grade and chronic inflammation in the adipose tissue, which further exacerbates metabolic dysfunctions. Understanding the mechanisms and immune cell types promoting this inflammation would allow for the d… Show more

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