T-cell non-Hodgkin lymphoma

Rizvi, Mujahid A.; Evens, Andrew M.; Tallman, Martin S.; Nelson, Beverly P.; Rosen, Steven T.

doi:10.1182/blood-2005-03-1306

Cited by 201 publications

(138 citation statements)

References 116 publications

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“…Angioimmunoblastic T-cell lymphoma (AITL) is one of the nodal peripheral T-cell lymphomas described in the WHO classification that accounts for 4-6% and 5% of all lymphomas in Western countries [1][2][3] and in Japan, 4 respectively. AITL typically presents with advanced stage disease, and is manifested by generalized lymphadenopathy, hepatosplenomegaly, and other systemic symptoms.…”

Section: Introductionmentioning

confidence: 99%

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Small Bowel Perforation Caused by Epstein-Barr Virus-Associated B Cell Lymphoma in a Patient with Angioimmunoblastic T-Cell Lymphoma

Takahashi

Maruyama

Mishima

et al. 2010

J Clin Exp Hematopathol

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On rare occasions, secondary Epstein-Barr virus (EBV)-associated B cell lymphoma can develop in a patient with angioimmunoblastic T-cell lymphoma (AITL). We report a case of a 66-year-old Japanese woman who developed diffuse large B-cell lymphoma (DLBCL) in her small intestine after chemotherapy for AITL. She was found to have panperitonitis due to perforation of the small intestine. Partial ileectomy specimen showed DLBCL cells infiltrating into the intestinal wall. In situ hybridization for EBV-encoded RNA revealed positivity in the lymphoma cells. The lymph nodes diagnosed as AITL were negative for EBV infection and there was no coexistence of B cell neoplasms in them. We thought small bowel perforation in this case was caused by EBV-associated B cell lymphoma secondary to AITL. Our case showed a remarkable deficiency of cellular immunity after chemotherapy, which we postulate was related to the cause of occurrence of B-cell lymphoma.

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Section: Introductionmentioning

confidence: 99%

“…Patients exhibit immunodeficiency secondary to the neoplastic process. [1][2][3] In the majority of cases, expansion of B-cells positive for EpsteinBarr virus (EBV) is seen, which is thought to be a consequence of underlying immune dysfunction. 5,6 It has been reported that supervening EBV-associated B cell lymphoma can occur in AITL.…”

Section: Introductionmentioning

confidence: 99%

Small Bowel Perforation Caused by Epstein-Barr Virus-Associated B Cell Lymphoma in a Patient with Angioimmunoblastic T-Cell Lymphoma

Takahashi

Maruyama

Mishima

et al. 2010

J Clin Exp Hematopathol

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“…Certain histological subtypes have been noted to have a relative predilection site as mucosaassociated lymphoid tissue (MALT) lymphoma in stomach, mantle cell lymphoma (MCL) in terminal ileum, jejunum and colon, as well as enteropathyassociated T-cell lymphoma (EATL) in jejunum, and follicular lymphoma (FL) in duodenum with a geographic variation in its distribution. 21 Multifocality, however, has been noticed particularly in MALT lymphoma and follicular lymphoma. Certain risk factors have been implicated in the pathogenesis of gastrointestinal lymphoma including Helico-bacter pylori (H. pylori) infection, human immunodeficiency virus (HIV), celiac disease, Campylobacter jejuni (C. jejuni), Epstein-Barr virus (EBV), hepatitis B virus (HBV), human T-cell lymphotropic virus-1 (HTLV-1), inflammatory bowel disease and immunosuppression.…”

Section: Discussionmentioning

confidence: 99%

Gastric lymphoma

Padala

Zhu

2016

Int J Res Med Sci

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“…The more common types are peripheral T cell lymphoma and angioimmunoblastic T cell lymphoma. All may present with B symptoms, rash, lymphadenopathy, hepatosplenomegaly, hemolytic anemia, and thrombocytopenia (11).…”

Section: Malignancymentioning

confidence: 99%