T Follicular Helper Cells in HIV Infection

Tackling HIV/AIDS - Are we there yet?

“…An Argentinian group has shown that AntibodyDependent Cellular Cytotoxicity (ADCC) has significant involvement in host immune response against HIV [18]. Van Lunzen et al from Germany found that T Follicular Helper cells (TFH) serve as reservoirs for HIV and support infection [19]. Another group from University of North Carolina has reported a broadly neutralizing antibody called 3B3 that is attached to a Pseudomonas-derived toxin, PE38, capable of activating cells in which HIV is hiding and kill them [20].…”