T helper-17 cells and T regulatory cells in vitiligo

Hamid, Mahmoud F. Abdel; Morsy, Safaa; Ela, Mostafa Abou El; Hegazy, Rehab A.; Fawzy, Marwa M.; Rashed, Laila A.; Omar, Ahmad Maliki; Fattah, Eman R. Abdel; Hany, Doaa M.

doi:10.7813/2075-4124.2013/5-6/a.34

Cited by 9 publications

(12 citation statements)

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“…This intermingling supports the paracrine interaction between the interrenal and chromaffin cells that is critical for controlling interrenal steroidogenesis (Bornstein et al, 1997). These results agree with the findings of other studies, in which the parenchyma of the adrenal gland in birds consists of an intermingling of adrenocortical cells (interrenal) and adrenomedullary cells (chromaffin) (Carsia, 2015) with no definite cortex and medulla (Fadl et al, 2023;Ghosh et al, 2001). Thus, the medulla of the gland is referred to as chromaffin tissue, and its cortex as interrenal (Carsia, 2015).…”

Section: Discussionsupporting

confidence: 88%

“…The adrenal glands are significant endocrine organs. In contrast to mammals, quails' adrenal glands lack a separate cortex and medulla, cortex is referred to as interrenal tissue and the medulla of the gland as chromaffin tissue (Fadl et al, 2023). The interrenal tissue in birds produces glucocorticoids and mineralocorticoids (Carsia, 2015).…”

Section: Introductionmentioning

confidence: 99%

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Prehatching development of the adrenal gland in Japanese quail (Coturnix japonica): Histological, immunohistochemical, and electron microscopic studies

Fadl,

Saleh,

Abou‐Elmagd

et al. 2023

Microscopy Res & Technique

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The adrenal glands play a key role in maintaining the physiological balance of birds and helping them to survive environmental changes. The objective of the present work was to give a detailed investigation of the histological, ultrastructural, and immunohistochemical findings of the adrenal gland in Japanese quail during the prehatching phase. The current study was performed on 45 healthy Japanese quail embryos at different prehatching periods. Our results showed the primordium of the quail's adrenocortical tissue appeared at 3 days of incubation as a thickening of the splanchnic mesoderm. The prospective chromaffin cells appeared at 5 days as clusters of cells migrated from the neural crest cells along the dorsal aorta toward the interrenal tissue. TH immunoreactivity was observed in the neural crest cells during their migration toward the adrenal primordium. Furthermore, these TH immunopositive cells were intermingled with the developing interrenal cell cords that developed from the coelomic epithelium. NSE immunostaining was detected within the cytoplasm of interrenal cells, chromaffin cells, and ganglion cells. Sox10 is expressed in chromaffin and ganglion cells with different staining intensities. On the 13th day of prehatching, both interrenal and chromaffin cells were β‐catenin immunonegative, but on the 17th day, both cells were immunopositively. Our findings show that during prenatal life, the adrenal gland undergoes significant morphological changes. Together, the present data suggest that studying the prenatal development of the adrenal gland in birds is important for advancing our understanding of this critical organ and its functions.Research Highlights The present study aimed to give a detailed study of the histological, ultrastructural, and immunohistochemical investigations of the adrenal gland in Japanese quail during the prehatching period. The interrenal primordium was observed on the third embryonic day, on the fifth ED the primordium of the chromaffin tissue appeared as row of migrating neural crest cell. At the ultrastructural level, the interrenal cells take steroid‐secreting cells characters, they have varying amounts of lipid droplets and abundant mitochondria at 15th ED contained moderate number of lysosomes and mitochondria.

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Section: Discussionsupporting

confidence: 88%

Section: Introductionmentioning

confidence: 99%

Prehatching development of the adrenal gland in Japanese quail (Coturnix japonica): Histological, immunohistochemical, and electron microscopic studies

Fadl,

Saleh,

Abou‐Elmagd

et al. 2023

Microscopy Res & Technique

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show abstract

“…Our results are in agreement with earlier studies that detected, the parenchyma of the adrenal gland in birds consists of an intermingling of adrenocortical cells (interrenal) and adrenomedullary cells (chromaffin) (Carsia, 2015) with no definite cortex and medulla (Fadl et al, 2023;Ghosh et al, 2001). In the current study, the quantity of interrenal tissue increased throughout the gland with age, especially at six weeks.…”

Section: Histological Examinationsupporting

confidence: 94%

Post‐hatching developmental changes in the adrenal gland of the Japanese quail (Coturnix coturnix japonica): Histological, immunohistochemical, and electron microscopic studies

Abdel-Maksoud

Abou-Elmagd

Saleh

2023

Microscopy Res & Technique

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The adrenal glands are paired abdominal endocrine organs vital to the bird's health. The present research aimed to provide a comprehensive examination of the histological, ultrastructural, and immunohistochemical investigations of the adrenal gland in Japanese quail during the post hatching period. The current study was performed on 21 healthy Japanese quail chicks at different post hatching periods. Our results showed the adrenal gland is surrounded by a connective tissue capsule, which consists of dense collagen fibers containing large blood vessels, chromaffin cells, autonomic ganglia, fibroblasts, and migrating Schwann cells. The zonation of the adrenal gland is composed of a subcapsular layer, a peripheral zone, and a central zone, which gets more pronounced with age. At the ultrastructural level, the interrenal cells take the steroid‐secreting cells characters; they have varying amounts of lipid droplets and abundant mitochondria. Adrenal medullary chromaffin cells showed positive immunoreactivity to the NSE. With increasing age, the chromaffin tissue's Sox10 immunoreactivity increased. β‐catenin is expressed within the plasmalemma and the cytoplasm of the interrenal and chromaffin cells and its reactivity increased with age, especially in the chromaffin cells. Our results indicate the adrenal gland undergoes significant morphological changes during the postnatal life. Overall, the postnatal period is an important time for the development and maturation of the adrenal glands.

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“…28 In addition, its transitionmetal ions, Co 2+ and Fe 3+ , can chelate electron donor atoms including O, N, and S from proteins, contributing to the immobilization process. 29 Recent studies have reported the synthesis of HA composites with cobalt ferrite using the microemulsion method, 13 the chronoamperometry technique, 30 the microwave-assisted wet precipitation method, 31 and the hydrothermal process. 32 However, in these works, the composites were synthesized for different applications, which did not include enzyme immobilization to be able to recover the enzyme from the reaction medium.…”

Section: Introductionmentioning

confidence: 99%

Hydroxyapatite-CoFe₂O₄ Magnetic Nanoparticle Composites for Industrial Enzyme Immobilization, Use, and Recovery

Coutinho

Malafatti

Paris

et al. 2020

ACS Appl. Nano Mater.

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Hydroxyapatite (HA) is an inorganic material with high ability to interact with proteins and has been recently explored as a support for enzyme immobilization. However, there are still some drawbacks concerning the recovery of these biocatalysts, which could be overcome using magnetic supports. Cobalt ferrite (CoFe 2 O 4 ) is a purely magnetic material, which offers excellent chemical stability, ease of synthesis, and mechanical hardness, being a promising candidate to form composites with HA and produce magnetic HA nanoparticles. Therefore, investigation of synthesis procedures and applications of HA/CoFe 2 O 4 composites to facilitate enzyme recovery by means of a magnetic field could find interest in a broad spectrum of biotechnological processes. Here, the co-precipitation method was used to synthesize HA/CoFe 2 O 4 composites with different HA/CoFe 2 O 4 mass ratios, for application as supports for enzyme immobilization. The enzymes β-glucosidase, phytase, and xylanase were selected for proof of concept due to their wide range of industrial applications. The composite with the highest cobalt ferrite content (2:1 mass ratio) was highly effective for immobilization of the three different enzymes, with immobilization yields (IYs) of 70−100% and recovered activities of 78−100%. The biocatalysts could be easily recovered from the reaction media by both centrifugation and application of an external magnetic field, demonstrating their potential for use in industrial processes. The materials exhibited good reusability, especially in the case of the βglucosidase biocatalyst, which could be reused 10 times, maintaining around 70% of its initial activity.

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T helper-17 cells and T regulatory cells in vitiligo

Cited by 9 publications

References 0 publications

Prehatching development of the adrenal gland in Japanese quail (Coturnix japonica): Histological, immunohistochemical, and electron microscopic studies

Prehatching development of the adrenal gland in Japanese quail (Coturnix japonica): Histological, immunohistochemical, and electron microscopic studies

Post‐hatching developmental changes in the adrenal gland of the Japanese quail (Coturnix coturnix japonica): Histological, immunohistochemical, and electron microscopic studies

Hydroxyapatite-CoFe₂O₄ Magnetic Nanoparticle Composites for Industrial Enzyme Immobilization, Use, and Recovery

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T helper-17 cells and T regulatory cells in vitiligo

Cited by 9 publications

References 0 publications

Prehatching development of the adrenal gland in Japanese quail (Coturnix japonica): Histological, immunohistochemical, and electron microscopic studies

Prehatching development of the adrenal gland in Japanese quail (Coturnix japonica): Histological, immunohistochemical, and electron microscopic studies

Post‐hatching developmental changes in the adrenal gland of the Japanese quail (Coturnix coturnix japonica): Histological, immunohistochemical, and electron microscopic studies

Hydroxyapatite-CoFe2O4 Magnetic Nanoparticle Composites for Industrial Enzyme Immobilization, Use, and Recovery

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Product

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Hydroxyapatite-CoFe₂O₄ Magnetic Nanoparticle Composites for Industrial Enzyme Immobilization, Use, and Recovery