Tachykinins

Severini, Cinzia; Improta, Giovanna

doi:10.1016/b978-0-12-385095-9.00055-5

Cited by 2 publications

(2 citation statements)

References 32 publications

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“…Frogs and giant salamander wastes (skin) are recognized as alternative collagenous or bioactive peptide (BP) sources, providing good physicochemical characteristics and bioactivities such as antioxidative [ 9 , 10 ], antimicrobial [ 5 , 11 , 12 ], anti-inflammatory [ 13 ], anticancer [ 12 ], antidiabetic [ 14 ], and drug delivery activities [ 15 ]. Several BPs have been isolated and studied from the skin of amphibians such as bradykinin [ 16 ], bombesin [ 17 ], bombinins [ 18 ], caeruleins [ 19 ], chromogranins/secretogranins [ 20 ], dermaseptins [ 21 ], tachykinins [ 22 ], and temporins [ 23 ]. Tigerinins from R. tigerina have been studied for their antimicrobial, wound healing, and antidiabetic properties [ 14 , 24 ].…”

Section: Introductionmentioning

confidence: 99%

Amphibian Skin and Skin Secretion: An Exotic Source of Bioactive Peptides and Its Application

Indriani

Karnjanapratum

Nirmal

et al. 2023

Foods

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Amphibians have been consumed as an alternative protein source all around the world due to their delicacy. The skin of edible amphibians, particularly frogs and giant salamanders, always goes to waste without further utilization. However, these wastes can be utilized to extract protein and bioactive peptides (BPs). Various BPs have been extracted and reported for numerous biological activities such as antioxidant, antimicrobial, anticancer, antidiabetic, etc. The main BPs identified were brevinins, bombesins, dermaseptins, esculentins, magainin, temporins, tigerinins, and salamandrins. This review provides a comprehensive discussion on various BPs isolated and identified from different amphibian skins or skin secretion and their biological activities. The general nutritional composition and production statues of amphibians were described. Additionally, multiple constraints against the utilization of amphibian skin and secretions are reported. Finally, the prospective applications of BPs in food and biomedical industries are presented such as multifunctional food additives and/or supplements as well as drug delivery agents.

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Section: Introductionmentioning

confidence: 99%

Amphibian Skin and Skin Secretion: An Exotic Source of Bioactive Peptides and Its Application

Indriani

Karnjanapratum

Nirmal

et al. 2023

Foods

View full text Add to dashboard Cite

show abstract

“…It was another 40 years before the amino acid sequence of substance P was confirmed. At that time, it was recognized that the sequence of substance P is similar to those of the tachykinins eledoisin and physalaemin, which were isolated from invertebrates [28]. Other endogenous tachyki nins (neurokinins A and B and hemokinin1) have been discovered more recently in vertebrates [19].…”

Section: Introductionmentioning

confidence: 99%