“…Trends Survey, only 10.2% of U.S. adults correctly answered that e-cigarettes are either less harmful or much less harmful than cigarettes, which may in part be driven by the wrongful attribution of nicotine e-cigarettes to lung injuries at the end of 2019 (Dave et al, 2020). The pervasive misperception that e-cigarettes are equally or more harmful than combustible cigarettes is a barrier to current smokers switching to e-cigarettes (Svenson et al, 2021). Raising the MLSA to 21 for both cigarettes and smokeless products could have the unintended effect of causing some substitution to cigarette use compared to the counterfactual world in which T21 could be adopted without changing perceptions of risk.…”