“…As regards sinusoidal macrophages, they may be required for the maintenance of homeostasis of hematopoietic niches with HSCs that are located in peri -sinusoidal areas [ 32 , 33 ]. Those macrophages that survived irradiation of lethal doses and chemotherapy drug treatments are supposed to be involved in restoration of HSC niches [ 33 ], and the role of AC particles in modulating this process could be critically important [ 34 ].…”