Tackling the Burden of Cardiovascular Diseases in India

Abdul-Aziz, Ahmad A.; Desikan, Prabha; Prabhakaran, Dorairaj; Schroeder, Lee F.

doi:10.1161/circoutcomes.118.005195

Cited by 46 publications

(33 citation statements)

References 7 publications

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“…It clears the fact that having these situations causes acute respiratory distress syndrome (ARDS) by SARS-CoV-2 pneumonia, requires a respiratory support system, and would not have died otherwise. The estimates suggest that more than 72 million people have diabetes, 54.5 million CVDs cases in the adult population of India (15, 16). In this position, the most challenging enigma is to divine the cumulative number of infected patients.…”

Section: Discussionmentioning

confidence: 99%

Recent update on COVID-19 in India: Is locking down the country enough?

Virk

Ali

Kaur

2020

Preprint

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Background: India is the second-largest population in the world, and it is not well equipped, hitherto, in the scenario of the global pandemic, SARS-CoV-2 could impart a devastating impact on the Indian population. Only way to respond against this critical condition is by practicing large-scale social distancing. India lock down for 21 days, however, till 7 April 2020, SARS-CoV-2 positive cases were growing exponentially, which raises the concerns if the number of reported and actual cases are similar. Methods: We use Lasso Regression withand Polynomial features of degree 2 to predict the growth factor. Also, we predicted Logistic curve using the Prophet Python. Further, using the growth rate to logistic, and carrying capacity is 20000 allowed us to calculate the maximum cases and new cases per day. Results:We found the predicted growth factor with a standard deviation of 0.3443 for the upcoming days. When the growth factor becomes 1.0, which is known as Inflection point, it will be safe to state that the rate is no longer exponential. The estimated time to reach the inflection point is between 15-20 April. At that time, the estimated number of total positive cases will be over 12500, if lockdown remains continue. Conclusions:Our analysis suggests that there is an urgent need to take action to extend the period of lockdown and allocate enough resources, including personnel, beds, and intensive care facilities, to manage the situation in the next few days and weeks. Otherwise, the outbreak in India can reach the level of the USA or Italy or could be worse than these countries within a few days or weeks, given the size of the population and lack of resources.

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Section: Discussionmentioning

confidence: 99%

Recent update on COVID-19 in India: Is locking down the country enough?

Virk

Ali

Kaur

2020

Preprint

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“…[ 1 ] Chronic breathlessness is particularly pertinent to resource-poor countries where urban air pollution, high smoking rates, and practices such as open fire cooking[ 14 ] contribute to a high prevalence of lung disease. [ 15 ] Respiratory disease occurs in approximately 7% of India's adult population,[ 14 16 ] and cardiovascular disease occurs in 54.5 million;[ 17 ] this translates into large absolute numbers given that 18% of the world's population lives in India,[ 18 ] and breathlessness is, therefore, likely to be a serious concern. Many breathlessness interventions are inexpensive, such as the hand-held fan[ 16 ] or breathing techniques training,[ 19 ] and thus potentially widely available.…”

Section: Introductionmentioning

confidence: 99%

How physicians in South India recognize, assess, and manage people with chronic breathlessness syndrome: A thematic analysis

Barnes-Harris

Daniel

Venkateswaran

et al. 2021

Indian J Palliat Care

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Objectives: Chronic breathlessness syndrome has been defined to help clinicians actively seek, and patients legitimately present with, persistent breathlessness, and to drive services and research. However, views from low- to middle-income countries were not included. We aimed to explore the views of hospital physicians regarding chronic breathlessness syndrome, its recognition and management. Methods: This was a secondary analysis of qualitative data collected during a service development project. Three focus groups of physicians caring for patients with chronic breathlessness in a single tertiary hospital in South India were conducted in English, audio-recorded, transcribed, and subjected to thematic analysis. Results: Fifteen physicians from oncology, palliative care, cardiology, and respiratory specialties participated. Three major themes (impact, invisibility, and purpose) were generated. Findings mirrored those in high-income countries. Chronic breathlessness, as defined, was seen as prevalent, with a major impact on patients, families, and physicians. Nonpalliative care physicians described therapeutic helplessness with poor awareness and/or ability to manage breathlessness accompanied by active avoidance. This helplessness, a perceived lack of assessment tools and lack of access to palliative care contributed to the “invisibility” of chronic breathlessness. Most participants agreed with the name of chronic breathlessness syndrome. All agreed that systematic identification would foster education regarding assessment and management and support service development and research. Conclusions: Chronic breathlessness syndrome is recognized in South India but, as in higher-income countries, risks being invisible due to the lack of awareness of therapeutic interventions. A named and defined syndrome was seen as a way to improve identification and management.

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“…Presently Cardiovascular disease is the leading cause of mortality in India and this has reached epidemic proportions. [1] In addition to the traditional risk factors of age, hypertension, diabetes mellitus etc, vitamin D Deficiency(VDD) is increasing being recognized to be associated with coronary artery disease and cardiovascular mortality and now considered as a risk factor for coronary atherosclerosis. [2,3] Also studies have shown that Vitamin D deficiency is associated with other cardiovascular comorbidites like diabetes mellitus, hypertension, dyslipidemia, obesity, peripheral vascular disease and heart failure.…”

Section: Introductionmentioning

confidence: 99%

Correlation of Vitamin D level with severity of Coronary Artery Disease(CAD) in patients of Acute Coronary Syndrome(ACS) in a Tertiary Care Centre in Western India

2021

IJFMT

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Background : Vitamin D deficiency (VDD) is a widespread problem in developing countries. Recent studies have shown association of Vitamin D deficiency with atherosclerosis and Coronary artery disease. This study was conducted to assess the relationship between Vitamin D and the severity of coronary artery disease (CAD) in patients undergoing coronary angiography. Materials and methods:Consecutive patients who underwent coronary angiography for acute coronary syndrome or effort angina were included in a descriptive cross-sectional study and their Vitamin D level was measured. CAD was defined as at least one vessel stenosis >50% on coronary angiography. Vitamin D levels were correlated to the CAG findings as to the severity and number of vessels involved and also to the traditional CAD risk factors Results: Vitamin D Deficiency was noted in 70.72% of the population in the study. Patients were classified as normal Vitamin D level(> 30ng/ml), Vitamin D insufficiency (20-30ng/ml) and Vitamin D Deficiency (<20ng/ml). Vitamin D levels had inversely correlated with significant coronary artery disease both for number of vessels involved and severity (p<0.001) and dyslipidemia(p=0.009). No significant association was found between VDD and other risk factors such as age, sex , hypertension, diabetes mellitus and smoking. Conclusion :Vitamin D deficiency was noted in majority of the patients undergoing CAG and was found to be significantly associated with the prevalence and severity of CAD. However studies involving larger population are needed to evaluate whether supplementation with vitamin D may help in prevention of atherosclerosis and further development of CAD.

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Tackling the Burden of Cardiovascular Diseases in India

Cited by 46 publications

References 7 publications

Recent update on COVID-19 in India: Is locking down the country enough?

Recent update on COVID-19 in India: Is locking down the country enough?

How physicians in South India recognize, assess, and manage people with chronic breathlessness syndrome: A thematic analysis

Correlation of Vitamin D level with severity of Coronary Artery Disease(CAD) in patients of Acute Coronary Syndrome(ACS) in a Tertiary Care Centre in Western India

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