Tacrolimus on Kimura's disease: a case report

Shu, Dalong; Wei, Ran; Guo, Bing; Zhang, Yunyan; Liu, Xiangzhen; Liao, Xianghai

doi:10.1016/j.oooo.2012.04.022

Cited by 12 publications

(5 citation statements)

References 11 publications

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“…The remission of proteinuria is well documented in MCD and mesangioproliferative glomerulonephritis. 31 Balwani et al also demonstrated remission of proteinuria and prevention of relapsing lymphadenopathy with low-dose tacrolimus (0.05 mg/kg/day). 32 Our patient did not achieve remission with oral corticosteroids for 6 weeks, which prompted the use of tacrolimus.…”

Section: Discussionmentioning

confidence: 96%

Membranous nephropathy with Kimura's disease: A case report and review of literature

Loganathan,

Mondal,

Basu

et al. 2024

Int J of Rheum Dis

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Kimura's disease (KD) is a chronic inflammatory disorder characterized by nontender lymphadenopathy involving the head and neck region. Renal involvement in KD is rare, especially in children. We report a 12‐year‐old boy who had been previously treated for classical KD and had presented with anasarca and oliguria after 4 years. There were no swellings or lymphadenopathy. The kidney biopsy revealed membranous nephropathy. Remission was achieved with oral prednisolone and tacrolimus therapy. This patient highlights the need to regularly monitor patients with KD for the evolution of renal diseases, even if lymphadenopathy regresses. Serial monitoring for eosinophilia, inflammatory markers, and urine examination is needed to help identify subclinical disease early and prompt initiation of specific therapy.

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Section: Discussionmentioning

confidence: 96%

Membranous nephropathy with Kimura's disease: A case report and review of literature

Loganathan,

Mondal,

Basu

et al. 2024

Int J of Rheum Dis

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“…3 Recently, a study showed the efficacy of tacrolimus on Kimura's disease. 10 The 2 previously reported patients with IgA nephropathy were treated with corticosteroids and showed significant decrease in proteinuria. 7,8 However, in the Vietnamese patient, a full-blown nephrotic syndrome rapidly recurred after steroids were tapered.…”

Section: Discussionmentioning

confidence: 99%

A Case of Immunoglobulin A Nephropathy in a Patient with Kimura's Disease

Park

Kim

et al. 2013

Yeungnam Univ J Med

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“…The analysis showed that surgical excision alone and radiotherapy alone had higher rates of local recurrence (Relative Risk: 4.722 and 2.718 respectively), compared to a combination of surgical excision and postoperative low dose irradiation. The use of immunosuppressive agents such as azathioprine (49), cyclosporin (49)(50)(51)(52)(53)(54), tacrolimus (55,56), methotrexate (57), mycophenolate mofetil (58,59), leflunomide (60,61), and cyclophosphamide (59,62) have been reported but also with variable outcomes. Cetirizine (63), an anti-allergy, omalizumab (64), an anti-IgE therapy and mepolizumab (65), an anti-interleukin-5 have also been used to treat Kimura disease with favourable outcomes.…”

Section: Discussionmentioning

confidence: 99%

Clinical Characteristics and Outcomes of Kimura Disease in Malaysia: A Case Series and a Literature Review

Gan,

Ng,

Yunus

et al. 2023

JUMMEC

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Kimura disease is a rare benign chronic inflammatory disorder of the soft tissue with predominant occurrences in young Asian male adults. However, there is limited information of Kimura disease in Southeast Asia. Hence, the clinical characteristics and outcomes of Kimura disease in Malaysia was investigated. Published Kimura disease cases from Malaysia were comprehensively searched in PubMed and Google Scholar up to December 2020 using the keywords “Kimura Disease” and “Malaysia”. Twenty-three papers were identified for review and case series of seven Kimura disease patients from a hospital in Malaysia were descriptively analyzed. A total of 60 cases were obtained from both sources. Eighty-seven percent were men with a male:female ratio of 6.5:1 and majority of the cases were Malays (77.1%). Median age of onset was 22.0 (IQR 12.5-31.5) years, while the median duration before diagnosis of Kimura disease was 2.0 (IQR 0.8-5.0) years. Head and neck region (95%) were the most frequently involved anatomical site. Peripheral eosinophilia was detected in 88.9% of the cases at presentation and renal involvement was observed in four (22.2%) patients. Surgery (57.5%) was the commonest first choice of treatment, followed by a combination of surgery and steroid (29.8%), steroid alone (10.6%), and a combination of steroid and immunosuppressive agent (2.1%). Local recurrences were observed in 28.6% of the cases. In conclusion, a much younger age of disease onset was found among Malaysians. A high recurrence rate of one in every four patients was observed, indicating the need for further evaluations of treatment strategies.

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Tacrolimus on Kimura's disease: a case report

Cited by 12 publications

References 11 publications

Membranous nephropathy with Kimura's disease: A case report and review of literature

Membranous nephropathy with Kimura's disease: A case report and review of literature

A Case of Immunoglobulin A Nephropathy in a Patient with Kimura's Disease

Clinical Characteristics and Outcomes of Kimura Disease in Malaysia: A Case Series and a Literature Review

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