Taenia solium Cysticercosis — The lessons of history

Brutto, Oscar H. Del; Garcı́a, Héctor H.

doi:10.1016/j.jns.2015.08.011

Cited by 53 publications

(47 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…2 There are numerous case series and case descriptions of patients with cysticercosis and epilepsy in the British and German literature from the late XIX and early XX Centuries, 3–5 but perhaps the most enlightening body of literature was crafted by medical officers of the British Army between 1932 and 1961, 6–9 where they described NCC as the cause of epilepsy in 450 British soldiers who were infected while on duty in India. From then on, thousands of NCC cases with seizures and epilepsy have been reported in medical journals.…”

Section: Association Between Neurocysticercosis and Seizuresmentioning

confidence: 99%

Antiparasitic treatment of neurocysticercosis - The effect of cyst destruction in seizure evolution

Garcı́a

Brutto

2017

Epilepsy & Behavior

Self Cite

View full text Add to dashboard Cite

Antiparasitic agents against Taenia solium cysticercosis are in use since 1979, although its use has been questioned on the basis that cysts would die naturally and thus treatment-induced inflammation is unnecessary. In addition, isolated reports have also questioned whether neurocysticercosis (NCC) is a cause of epilepsy. After more than three and a half decades, a large body of evidence is available. Little if any doubt exists on NCC as a cause of seizures - NCC is consistently associated with seizures when appropriate groups are compared, and in a large subset of cases, seizure semiology correlates with the anatomical location of lesions. Cyst degeneration and the subsequent inflammatory reaction increase seizure expression, although patients with non-inflamed cysts may show seizures, as do patients with long-standing, not inflamed calcified scars. Assessment of the evidence on cysticidal efficacy, safety, and the impact of cyst destruction in decreasing seizures leads to conclude that the benefits of antiparasitic treatment in parenchymal brain cysticercosis clearly overcome the risks, and have provided substantive evidence of the role of NCC as a cause of seizures and epilepsy. Antiparasitic therapy should be considered a primary option in the management of patients with live or degenerating brain NCC cysts.

show abstract

Section: Association Between Neurocysticercosis and Seizuresmentioning

confidence: 99%

Antiparasitic treatment of neurocysticercosis - The effect of cyst destruction in seizure evolution

Garcı́a

Brutto

2017

Epilepsy & Behavior

Self Cite

View full text Add to dashboard Cite

show abstract

“…Pero no será hasta mediados del siglo XIX cuando patólogos alemanes, Küchenmeister (1855) y Leuckart (1856), identifiquen a Taenia solium como la misma causa de la teniasis intestinal y la cisticercosis, cerrando su ciclo biológico. Los brotes de NCC en soldados repatriados de la India a Reino Unido en el siglo XX o la epidemia en Papúa Guinea tras la importación de cerdos desde Indonesia en la década de 1970-1980, son una muestra de que la NCC puede manifestarse años después de la infestación 14,15 . La OMS considera que la NCC es la parasitación cerebral más frecuente en el mundo y la primera causa prevenible de epilepsia.…”

Section: Epidemiologíaunclassified

Neurocisticercosis: Una Enfermedad Que No Debemos Olvidar.

Fernández-Rodríguez¹,

Fernández²,

Deltell³

2017

Gal. Clin.

View full text Add to dashboard Cite

La cisticercosis es una infección causada por Cysticercus cellulosae, la larva del helminto Taenia solium o "tenia del cerdo". Taenia solium puede producir dos formas de infección: Teniasis intestinal (tenias maduras) e infestación por cisticercos que anidan en distintos órganos y tejidos. Es frecuente la localización de los cisticercos en el Sistema Nervioso Central (SNC) causando la Neurocisticercosis (NCC) 1-4. La NCC es muy prevalente en países subdesarrolados; la OMS la considera como la parasitación cerebral más frecuente en el mundo y la más importante causa prevenible de epilepsia. Es excepcional en países desarrollados como España pero ha resurgido en la últimas décadas en relación con la inmigración desde zonas endémicas y con los viajes. El propósito de esta revisión es comentar los avances recientes sobre aspectos de la NCC tanto epidemiológicos como relativos a la inmunopatogenia, sus manifestaciones clínicas, su diagnóstico y tratamiento. También tiene el fin de hacer una llamada a los profesionales sanitarios para no olvidar la NCC, pues aún hay enfermos autóctonos y existe un mayor número de casos, que es previsible que se incremente, en inmigrantes, viajeros y ciudadanos que conviven con ellos.

show abstract

“…remedies have been still researched today for possible anthelmintic proprieties. 9,10,11 Even though the Romans had developed better hygiene standards with flushing latrines and running water, helminthiasis must have been a major public health issue in the Roman Period when Galen lived and practiced. 12 Since the ancient Greeks had noticed the connection between pork and the parasites, it is supported that this belief was the original inspiration behind the prohibition of pork consumption in the Quran.…”

Section: Introductionmentioning

confidence: 99%

On the Work of Alexander of Tralles

Kripouri

Filippou

2019

AMHA

View full text Add to dashboard Cite

Helminthiasis is known to man since antiquity, but it still remains a significant public health problem. In ancient times many plants have been tried as possible therapeutics in search of an effective drug. This manuscript investigates ancient beliefs on parasitic worm infestation. Moreover, Alexander of Tralles’ (525 – 605 CE) suggestions on the treatment of this condition are discussed as found in his lesser-known work “A letter on helminths”, along with comments on the use of those herbal cures by modern medicine.

show abstract

Taenia solium Cysticercosis — The lessons of history

Cited by 53 publications

References 32 publications

Antiparasitic treatment of neurocysticercosis - The effect of cyst destruction in seizure evolution

Antiparasitic treatment of neurocysticercosis - The effect of cyst destruction in seizure evolution

Neurocisticercosis: Una Enfermedad Que No Debemos Olvidar.

On the Work of Alexander of Tralles

Contact Info

Product

Resources

About