Taeniasis among Refugees Living on Thailand–Myanmar Border, 2012

McCleery, Ellen; Patchanee, Prapas; Pongsopawijit, Pornsawan; Chailangkarn, Sasisophin; Tiwananthagorn, Saruda; Jongchansittoe, Papaspong; Dantrakool, Anchalee; Morakote, Nimit; Phyu, Hnin; Wilkins, Patricia P.; Noh, John; Phares, Christina R.; O’Neal, Seth E.

doi:10.3201/eid2110.141657

Cited by 16 publications

(15 citation statements)

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“…However it must be stressed that this is currently still a speculative (and optimistic) assessment of a potential intervention. Although there currently are tests for detection of stage-specific human T. solium taeniasis antibodies and neurocysticercosis antibodies [ 43 ] that have been used in a number of field studies [ 44 , 45 ], barriers exist to the introduction and financing of such an intervention on a large scale. The efficacy of a human test & treat strategy would also be influenced by the level of (taeniasis-cysticercosis) co-infection in the community, with high levels of co-infection hampering success.…”

Section: Discussionmentioning

confidence: 99%

“…We are able to make a number of recommendations to facilitate progress towards the 2015 and the 2020 goals laid out in the WHO NTD roadmap [ 2 ] and that support those made by an expert panel to the WHO in 2011 [ 55 ]. Firstly, the potential for a human test & treat strategy to be highly effective supports calls for the prioritisation of further research into the development of affordable, fast and accurate point-of-care diagnostics to distinguish between taeniasis and cysticercosis [ 43 – 45 ]. Secondly, pig MDA or pig vaccination is capable of effecting a significant impact on averting human cysticercosis at present, warranting their further evaluation in large-scale field trials.…”

Section: Discussionmentioning

confidence: 99%

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Assessing the impact of intervention strategies against Taenia solium cysticercosis using the EPICYST transmission model

et al. 2017

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BackgroundThe pork tapeworm, Taenia solium, and associated human infections, taeniasis, cysticercosis and neurocysticercosis, are serious public health problems, especially in developing countries. The World Health Organization (WHO) has set goals for having a validated strategy for control and elimination of T. solium taeniasis/cysticercosis by 2015 and interventions scaled-up in selected countries by 2020. Timely achievement of these internationally-endorsed targets requires that the relative benefits and effectiveness of potential interventions be explored rigorously within a quantitative framework.MethodsA deterministic, compartmental transmission model (EPICYST) was developed to capture the dynamics of the taeniasis/cysticercosis disease system in the human and pig hosts. Cysticercosis prevalence in humans, an outcome of high epidemiological and clinical importance, was explicitly modelled. A next generation matrix approach was used to derive an expression for the basic reproduction number, R 0. A full sensitivity analysis was performed using a methodology based on Latin-hypercube sampling partial rank correlation coefficient index.ResultsEPICYST outputs indicate that chemotherapeutic intervention targeted at humans or pigs would be highly effective at reducing taeniasis and cysticercosis prevalence when applied singly, with annual chemotherapy of humans and pigs resulting, respectively, in 94 and 74% of human cysticercosis cases averted. Improved sanitation, meat inspection and animal husbandry are less effective but are still able to reduce prevalence singly or in combination. The value of R 0 for taeniasis was estimated at 1.4 (95% Credible Interval: 0.5–3.6).ConclusionsHuman- and pig-targeted drug-focussed interventions appear to be the most efficacious approach from the options currently available. The model presented is a forward step towards developing an informed control and elimination strategy for cysticercosis. Together with its validation against field data, EPICYST will be a valuable tool to help reach the WHO goals and to conduct economic evaluations of interventions in varying epidemiological settings.Electronic supplementary materialThe online version of this article (doi:10.1186/s13071-017-1988-9) contains supplementary material, which is available to authorized users.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Assessing the impact of intervention strategies against Taenia solium cysticercosis using the EPICYST transmission model

et al. 2017

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“…Sayur-sayuran serta umbi-umbian yang ikut dimasak dengan cara bakar batu panas kadangkala terkontaminasi dengan tanah di lingkungan sehingga besar kemungkinan tercemar oleh telur Taenia solium. 17,34,35 Konsumsi sayuran-sayuran mentah dan daging babi yang kurang matang yang terkontaminasi telur dan larva cacing pita merupakan sumber penularan sistiserkosis dan taeniasis. 36 Gejala taeniasis pada manusia biasanya asimptomatis, namun pada infeksi berat dapat menyebabkan malnutrisi.…”

Section: Pertimbangan Etik Penelitianunclassified

Faktor-Faktor Risiko yang Berhubungan dengan Kejadian Taeniasis dan Sistiserkosis di Papua Barat

Sandy

Sasto

Fitriana

et al. 2019

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Taeniasis and cysticercosis are zoonotic diseases pigs and still become a health problem in West Papua. In 2003-2004, the prevalence of taeniasis was 4.1% and cysticercosis 2.3%. The aim of the study was to determine the prevalence and determinants of transmission of the disease. A cross-sectional design was carried out in March-December 2016, with 1,489 of respondents. Data was collected through fingertip blood collection and interviews for determinant factors of taeniasis transmission and cysticercosis. Examination of blood samples was carried out using magnetic microparticle immunoassay. The results of the study on taeniasis proportion were 3.0% (n=1.489) and taeniasis determinant factors were education [RR=1.3; CI 95% (0.695-2.418); p=0.047], hand washing habits before eating [RR=12.3; CI 95% (5.857-25.853); p=0.0001], habit of washing hands after defecate (p=0.0001), consuming vegetables (p=0.0001), vegetables being washed in the river [RR=0.3; CI 95% (0.153-0.674); p=0.002] and consumption of roast meat [RR=0.3; CI 95% (0.166-0.570); p=0.0001]. The proportion of cysticercosis is 3.2% (n=1,489). and cysticercosis determinant factors are education [RR=0.3; CI 95% (0.162-0.819); p=0.011], hand washing habits before eating [RR=2.4; CI 95% (1.344-4.351); p=0.002], the habit of washing hands after defecate [RR=3.2; 95% CI (1.787-5.809); p=0.0001], nail hygiene [RR=2.8 CI 95% (1.415-5.546); p=0.002], consumption of vegetables [RR=0.3; CI 95% (0.179-0.577); p=0,0001], vegetables are washed in the river [RR=0.4; CI 95% (0.222-0.837); p=0.012]. Determinant factors of Taeniasis and cysticercosis were education level, hand washing, nail hygiene, consumption of vegetables, washing vegetables in the river and consumption of roasted meat. It is crucial to provide education to community about clean,healthy behavior, and consumption of cooked meat.

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“…Recently, epidemiologic studies of taeniasis in Myanmar have been performed; however, they focused on T. solium cysticercosis in pigs in Nay Pyi Taw area and seropositivity of refugee camp residents on the Thailand–Myanmar border ( 3 , 4 ). A report of T. saginata in Myanmar described only an experimental infection in animals, not human infections ( 5 ).…”

mentioning

confidence: 99%

Molecular Diagnosis of Taenia saginata Tapeworm Infection in 2 Schoolchildren, Myanmar

Won¹,

Jung²,

Song³

et al. 2018

Emerg. Infect. Dis.

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Taeniasis among Refugees Living on Thailand–Myanmar Border, 2012

Cited by 16 publications

References 12 publications

Assessing the impact of intervention strategies against Taenia solium cysticercosis using the EPICYST transmission model

Assessing the impact of intervention strategies against Taenia solium cysticercosis using the EPICYST transmission model

Faktor-Faktor Risiko yang Berhubungan dengan Kejadian Taeniasis dan Sistiserkosis di Papua Barat

Molecular Diagnosis of Taenia saginata Tapeworm Infection in 2 Schoolchildren, Myanmar

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