Tai Chi and other mind–body interventions for cancer-related fatigue: an updated systematic review and network meta-analyses protocol

Abstract

IntroductionFatigue is one of the most common symptoms in patients with cancer and is responsible for a reduced quality of life. There is a strong evidence base for mind–body interventions (MBIs) to manage cancer-related fatigue (CRF). However, the efficacy of Tai Chi and other MBIs in the treatment of CRF remains controversial.Methods and analysisWe will perform a systematic review and network meta-analyses (NMAs) that aim to assess the effects of Tai Chi and other MBIs in patients with CRF. The following databases will be searched from their inception to 1 August 2021: PubMed, EMBASE, Scopus, OVID, Web of Science, Cochrane Central Register of Controlled Trials, the China National Knowledge Infrastructure, China Science and Technology Journal Database, Chinese Biomedical Database and Wan Fang Digital Journals. We will include randomised controlled trials that compare MBIs with no treatment, placebo and usual care in the treatment of CRF. The primary outcome will be changes in the fatigue state as evaluated by validated scales. We will perform a Bayesian NMA to analyse all the evidence for each outcome. The surface under the cumulative ranking curve and the mean ranks will be used to rank the various treatments. We will assess the quality of evidence contributing to network estimates of outcomes using the Grading of Recommendations Assessment, Development and Evaluation system framework.Ethics and disseminationThis NMAs will be disseminated through publication in a peer-reviewed journal. Since no individual patient data will be involved in the review, ethics approval and concerns about privacy are not needed.PROSPERO registration numberCRD42021244999.

Nonpharmacological interventions for cancer-related fatigue: A comprehensive literature review

“…As for other TCM therapies, studies have shown that Tai Chi, Tai Chi Sword, Qigong, Baduanjin (eight-sectioned exercise), and Wuqinxi (five mimic-animal exercise) can also relieve CRF in cancer patients to a certain extent 77 , 78 . But considering the quality and quantity of the existing literature, trials of higher quality and larger sample sizes are needed to further validate their therapeutic effects in the future.…”

Multi-Institutional Analysis of Cancer Patient Exposure, Perceptions, and Trust in Information Sources Regarding Complementary and Alternative Medicine

“…1 Although some mind-body interventions have been shown to improve the subjective well-being of patients with cancer, none have been shown to be an effective cure for cancer. [2][3][4] A recent publication identifies various CAM with evidence of efficacy for cancer-related pain. 5 By contrast, observational reports suggest a lower survival among patients with cancer using complementary or alternative therapies as part of cancer treatment.…”

“…We report the results of a cross-sectional survey of adult patients with cancer treated at a large, regional nonprofit cancer center and a National Cancer Institute (NCI)-designated Comprehensive Cancer Center between 2020 and 2021 to characterize the following: (1) rates of CAM use, (2) perceptions and attitudes regarding CAM therapy, (3) sources of exposure to CAM, and (4) trust in these sources. By characterizing cancer patient practices, perspectives, exposure, and trust regarding CAM, we aim to inform future research on provider clinician-communication and develop novel approaches to address the effects of misinformation exposure on patients with cancer.…”

Adaptação transcultural e validade de conteúdo do Multidimensional Fatigue Inventory–10 para o português do Brasil

“…Em pacientes oncológicos, a fadiga é um dos sintomas mais prevalentes, acometendo entre 14,03% a 100% dos casos, a depender do grupo de pacientes estudados [3][4][5] . No entanto, apesar do reconhecimento de sua alta prevalência ____________________ Manuscrito proveniente da dissertação intitulada: "Adaptação transcultural do Multidimensional Fatigue Inventory -10 para o idioma português do Brasil", Programa de Pós-Graduação em Enfermagem da Universidade Federal de Juiz de Fora, Juiz de Fora, MG, Brasil, 2021.…”

“…Rev enferm UERJ, Rio de Janeiro, 2022; 30:e66073 p.2 tal manifestação não é sempre rastreada com precisão em oncologia 5 . Estudos apontam que devido a subjetividade e a dificuldade dos pacientes em relatar os sintomas, a fadiga é subnotificada pelos profissionais de saúde 1,4,5 .…”