The dependence of optical properties on the ambient medium, the period of nanohole arrays and the metal film thickness in a thick silver film perforated with rectangular nanohole arrays is investigated using the finite‐difference time‐domain technique. As a result of the coupling between top and down surface plasmon polaritons, mediated by localized surface plasmon resonances supported by the metallic rectangular nano‐ holes, interesting light phenomena are observed for varying thickness of the metal film and period of the rectangular nanohole arrays. Based on the dependence of the optical properties on the ambient medium, the possibility of exploiting thick metal rectangular nanohole arrays as plasmonic sensors is further discussed, the potential application as plasmonic sensors is revealed. (© 2013 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)